About: High- and low-affinity sites for sodium in delta-OR-G(i)1 alpha (Cys(351)-Ile(351)) fusion protein stably expressed in HEK293 cells; functional significance and correlation with biophysical state of plasma membrane

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About: High- and low-affinity sites for sodium in delta-OR-G(i)1 alpha (Cys(351)-Ile(351)) fusion protein stably expressed in HEK293 cells; functional significance and correlation with biophysical state of plasma membrane Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The effect of monovalent cations on delta-opioid receptor ligand binding parameters and coupling with the cognate G protein was compared in model HEK293 cell line stably expressing PTX-insensitive delta OR Gi1alpha (Cys351-Ile351) fusion protein. The possible differences between individual ions when interacting with the polar membrane-water interface and the hydrophobic interior of membrane bilayer was studied with help of fluorescence probes The effect of monovalent cations on delta-opioid receptor ligand binding parameters and coupling with the cognate G protein was compared in model HEK293 cell line stably expressing PTX-insensitive delta OR Gi1alpha (Cys351-Ile351) fusion protein. The possible differences between individual ions when interacting with the polar membrane-water interface and the hydrophobic interior of membrane bilayer was studied with help of fluorescence probes (en)
Title	High- and low-affinity sites for sodium in delta-OR-G(i)1 alpha (Cys(351)-Ile(351)) fusion protein stably expressed in HEK293 cells; functional significance and correlation with biophysical state of plasma membrane High- and low-affinity sites for sodium in delta-OR-G(i)1 alpha (Cys(351)-Ile(351)) fusion protein stably expressed in HEK293 cells; functional significance and correlation with biophysical state of plasma membrane (en)
skos:prefLabel	High- and low-affinity sites for sodium in delta-OR-G(i)1 alpha (Cys(351)-Ile(351)) fusion protein stably expressed in HEK293 cells; functional significance and correlation with biophysical state of plasma membrane High- and low-affinity sites for sodium in delta-OR-G(i)1 alpha (Cys(351)-Ile(351)) fusion protein stably expressed in HEK293 cells; functional significance and correlation with biophysical state of plasma membrane (en)
skos:notation	RIV/67985823:_____/14:00428435!RIV15-GA0-67985823
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GAP207/12/0919), P(GBP304/12/G069)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Svoboda, Petr Vošahlíková, Miroslava Roubalová, Lenka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	19045
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/14:00428435
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	delta - opioid receptor; monovalent ions; agonist and antagonist binding; [35S]GTPγS binding; membrane biophysics; Laurdan fluorescence (en)
http://linked.open.../riv/klicoveSlovo	[35S]GTPγS binding Laurdan fluorescence agonist and antagonist binding delta membrane biophysics monovalent ions
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[7909644E50B7]
http://linked.open...i/riv/nazevZdroje	Naunyn-Schmiedeberg's Archives of Pharmacology
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Project of excellence in the field of neuroscience The role of hydrophobic plasma membrane interior in DOR regulation of trimeric G protein activity
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	387
http://linked.open...iv/tvurceVysledku	Hof, Martin Jurkiewicz, Piotr Svoboda, Petr Roubalová, Lenka Vošahlíková, Miroslava
http://linked.open...ain/vavai/riv/wos	000334512800010
issn	0028-1298
number of pages	16 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s00210-014-0962-8

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