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  • Five pathogenic Candida species were compared in terms of their osmotolerance, tolerance to toxic sodium and lithium cations, and resistance to fluconazole. we show that the fluconazole treatment of growing cells of all five species results in a substantial hyperpolarization of their plasma membranes, which is responsible for an increased non-specific transport of toxic alkali metal cations and other cationic drugs
  • Five pathogenic Candida species were compared in terms of their osmotolerance, tolerance to toxic sodium and lithium cations, and resistance to fluconazole. we show that the fluconazole treatment of growing cells of all five species results in a substantial hyperpolarization of their plasma membranes, which is responsible for an increased non-specific transport of toxic alkali metal cations and other cationic drugs (en)
Title
  • Fluconazole treatment hyperpolarizes the plasma membrane of Candida cells
  • Fluconazole treatment hyperpolarizes the plasma membrane of Candida cells (en)
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  • Fluconazole treatment hyperpolarizes the plasma membrane of Candida cells
  • Fluconazole treatment hyperpolarizes the plasma membrane of Candida cells (en)
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  • RIV/67985823:_____/13:00397981!RIV14-GA0-67985823
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  • I, P(GAP302/12/1151), Z(AV0Z50110509)
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  • 8
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  • 75336
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  • RIV/67985823:_____/13:00397981
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  • drug resistance; fluconazol; yeast; hyperpolarization (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [C9A7C3A47184]
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  • Medical Mycology
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  • 51
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  • Sychrová, Hana
  • Elicharová, Hana
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  • 000325891200001
http://linked.open...n/vavai/riv/zamer
issn
  • 1369-3786
number of pages
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  • 10.3109/13693786.2013.779038
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