About: Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat

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About: Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	To uncover possible genetic determinants of coronary microvascular remodeling, we carried out detailed histological and histomorphometric analysis of the heart and coronary vasculature in 30 weeks old SHR, age-matched Brown Norway (BN-Lx) parentals and BXH/HXB recombinant inbred (RI) strains. Using previously mapped expression quantitative trait loci (eQTLs), we carried out a genomewide association analysis and identified genetic determinants of cardiac gene expression and histomorphometric traits To uncover possible genetic determinants of coronary microvascular remodeling, we carried out detailed histological and histomorphometric analysis of the heart and coronary vasculature in 30 weeks old SHR, age-matched Brown Norway (BN-Lx) parentals and BXH/HXB recombinant inbred (RI) strains. Using previously mapped expression quantitative trait loci (eQTLs), we carried out a genomewide association analysis and identified genetic determinants of cardiac gene expression and histomorphometric traits (en)
Title	Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat (en)
skos:prefLabel	Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat (en)
skos:notation	RIV/67985823:_____/13:00392087!RIV14-MSM-67985823
http://linked.open...avai/predkladatel	Fyziologický ústav AV ČR, v.v.i.
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GAP301/12/0696), P(LH11049), P(LL1204)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Šilhavý, Jan Zídek, Václav Pravenec, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	86267
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/13:00392087
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	arterial hypertension; coronary circulation; myocardial ischemia; spontaneously hypertensive rat; recombinant inbred strains (en)
http://linked.open.../riv/klicoveSlovo	coronary circulation recombinant inbred strains arterial hypertension spontaneously hypertensive rat myocardial ischemia
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[4815D5E29E22]
http://linked.open...i/riv/nazevZdroje	Basic Research in Cardiology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	11 (xsd:int)
http://linked.open...vavai/riv/projekt	Transgenic rescue analysis of down-regulated genes involved in catecholamine biosynthesis in adrenal medulla of the spontaneously hypertensive rat Genetic analysis of mitochondrial proteome: Integration of mitochondrial-nuclear epistasis with disease phenotypes in the rat Genetic determinants of interstitial fibrosis and coronary microvascular remodelation
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	108
http://linked.open...iv/tvurceVysledku	Cook, S. Pravenec, Michal Zídek, Václav Šilhavý, Jan Mancini, M. Petretto, E. Camici, P. G. De, T. Kleinert, C. Scavone, A. d´Amati, G.
http://linked.open...ain/vavai/riv/wos	000314641700008
issn	0300-8428
number of pages	14 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s00395-012-0316-y

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