About: How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels

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About: How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In our study, we present a novel p(chi2) (chi-square) method for evaluating the anisotropy of line systems that involves comparing the observed length densities of lines with the discrete uniform distribution of an isotropic line system with the chi2-test. Using this method in our open source software, we determined the rose of directions, preferential directions and level of anisotropy of linear systems representing the microscopic blood vessels in samples of various regions from human brains (cortex, subcortical gray matter and white matter). The novel method was compared with two other methods used for anisotropy quantification (ellipsoidal and fractional anisotropy). All three methods detected different levels of anisotropy of blood microvessels in human brain. The microvascular bed in the cortex was closer to an isotropic network, while the microvessels supplying the white matter appeared to be an anisotropic and direction-sensitive system In our study, we present a novel p(chi2) (chi-square) method for evaluating the anisotropy of line systems that involves comparing the observed length densities of lines with the discrete uniform distribution of an isotropic line system with the chi2-test. Using this method in our open source software, we determined the rose of directions, preferential directions and level of anisotropy of linear systems representing the microscopic blood vessels in samples of various regions from human brains (cortex, subcortical gray matter and white matter). The novel method was compared with two other methods used for anisotropy quantification (ellipsoidal and fractional anisotropy). All three methods detected different levels of anisotropy of blood microvessels in human brain. The microvascular bed in the cortex was closer to an isotropic network, while the microvessels supplying the white matter appeared to be an anisotropic and direction-sensitive system (en)
Title	How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels (en)
skos:prefLabel	How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels (en)
skos:notation	RIV/67985823:_____/11:00365082!RIV12-AV0-67985823
http://linked.open...avai/predkladatel	Fyziologický ústav AV ČR, v.v.i.
http://linked.open...avai/riv/aktivita	O P Z
http://linked.open...avai/riv/aktivity	O, P(ED1.1.00/02.0090), P(GA106/09/0740), P(GP106/09/P226), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Janáček, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	202810
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/11:00365082
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	rose of directions; preferential directions; chi-square test; length density; python (en)
http://linked.open.../riv/klicoveSlovo	chi-square test length density preferential directions python rose of directions
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[202314823309]
http://linked.open...i/riv/nazevZdroje	Journal of Theoretical Biology
http://linked.open...in/vavai/riv/obor	EA
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Microstructure oriented hierarchical modeling of brain perfusion for CT based cerebral blood flow evaluation NTIS - New Technologies for Information Society Development of software with graphical user interface for evaluation of mechanical measurements performed on soft biological tissues
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	286
http://linked.open...iv/tvurceVysledku	Janáček, Jiří Cimrman, R. Kochová, P. Tonar, Z. Witter, K.
http://linked.open...ain/vavai/riv/wos	000294975800008
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka
issn	0022-5193
number of pages	12 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.jtbi.2011.07.004
is http://linked.open...avai/riv/vysledek of	How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels

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