About: Early postnatal development of rat brain is accompanied by generation of lipofuscin-like pigments     Goto   Sponge   NotDistinct   Permalink

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  • The increased generation of free radicals results in the formation of fluorescent end-products of lipid peroxidation, lipofuscin-like pigments (LFPs). The authors observed that LFPs are generated in rat brain after a normal birth during 5 postnatal days. Maximum LFP concentration is achieved on the postnatal day 2. Starting from postnatal day 10, LFP concentration returns to prenatal values. A new rise in LFP concentration is observed at 3 months of age. This is associated with the beginning of the aging process. The authors suggest that LFPs are formed after respiratory burst of microglia phagocytosing apoptotic cells
  • The increased generation of free radicals results in the formation of fluorescent end-products of lipid peroxidation, lipofuscin-like pigments (LFPs). The authors observed that LFPs are generated in rat brain after a normal birth during 5 postnatal days. Maximum LFP concentration is achieved on the postnatal day 2. Starting from postnatal day 10, LFP concentration returns to prenatal values. A new rise in LFP concentration is observed at 3 months of age. This is associated with the beginning of the aging process. The authors suggest that LFPs are formed after respiratory burst of microglia phagocytosing apoptotic cells (en)
Title
  • Early postnatal development of rat brain is accompanied by generation of lipofuscin-like pigments
  • Early postnatal development of rat brain is accompanied by generation of lipofuscin-like pigments (en)
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  • Early postnatal development of rat brain is accompanied by generation of lipofuscin-like pigments
  • Early postnatal development of rat brain is accompanied by generation of lipofuscin-like pigments (en)
skos:notation
  • RIV/67985823:_____/11:00365079!RIV12-AV0-67985823
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  • P(IAA500110606), P(LC554), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika
  • 1-2
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http://linked.open...aciTvurceVysledku
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  • 195895
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/11:00365079
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  • brain; early development; lipofuscin-like pigments; fluorescence; rat (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [D754EA2C651D]
http://linked.open...i/riv/nazevZdroje
  • Molecular and Cellular Biochemistry
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  • 347
http://linked.open...iv/tvurceVysledku
  • Svoboda, Petr
  • Ivica, J.
  • Kagan, Dmytro
  • Wilhelm, J.
http://linked.open...ain/vavai/riv/wos
  • 000285421500017
http://linked.open...n/vavai/riv/zamer
issn
  • 0300-8177
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s11010-010-0623-2
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