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rdf:type
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Description
| - Toto review shrnuje naše poznatky ohledně kmenových buněk a také elastické efekty léků na nádorové a hladké svalové buňky. Léky obsahují inhibitor kontrakce blebbistatin, proliferační ihibitor mitomycin C, apoptozu indukující protilátku proti CD47 a inhibitor translace cycloheximid. Diferenciační efekty nejenže zasahují do citlivosti buněk vůči substrátu, ale také mají významné důsledky pro regeneraci a molekulární terapii (cs)
- This review summarizes our initial findings for multipotent stem cells and also the elasticity-coupled effects of drugs on cancer cells and smooth muscle cells. The drugs include the contractility inhibitor blebbistatin, the proliferation inhibitor mitomycin C, an apoptotis-inducing antibody against CD47, and the translation inhibitor cycloheximide. The differential effects not only lend insight into mechano-sensing of the substrate by cells, but also have important implications for regeneration and molecular therapies
- This review summarizes our initial findings for multipotent stem cells and also the elasticity-coupled effects of drugs on cancer cells and smooth muscle cells. The drugs include the contractility inhibitor blebbistatin, the proliferation inhibitor mitomycin C, an apoptotis-inducing antibody against CD47, and the translation inhibitor cycloheximide. The differential effects not only lend insight into mechano-sensing of the substrate by cells, but also have important implications for regeneration and molecular therapies (en)
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Title
| - Cell responses to the mechanochemical microenvironment—Implications for regenerative medicine and drug delivery
- Cell responses to the mechanochemical microenvironment—Implications for regenerative medicine and drug delivery (en)
- Buňka odpovídá na mechanochemické mikroprostředí-důsledky pro lékařství a cílené léky (cs)
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skos:prefLabel
| - Cell responses to the mechanochemical microenvironment—Implications for regenerative medicine and drug delivery
- Cell responses to the mechanochemical microenvironment—Implications for regenerative medicine and drug delivery (en)
- Buňka odpovídá na mechanochemické mikroprostředí-důsledky pro lékařství a cílené léky (cs)
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skos:notation
| - RIV/67985823:_____/07:00311977!RIV09-AV0-67985823
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1M0510), Z(AV0Z50110509)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/67985823:_____/07:00311977
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - cells; tissue regeneration; drug delivery (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Advanced Drug Delivery Reviews
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Eckhardt, Adam
- Discher, D. E.
- Engler, A. J.
- Fariyal, C.
- Rehfeldt, F.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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is http://linked.open...avai/riv/vysledek
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