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rdf:type
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Description
| - Simultaneous administration of N-acetylcysteine prevented the development of NO-deficient hypertension in rats chronically treated with L-NAME (50 mg/kg/day). Lowering of oxygen radical production and/or their action on cell membranes was accompanied by partial restoration of NO synthase activity attenuated by chronic L-NAME treatment. N-acetylcysteine has better preventive than therapeutic effects, because it has only minimal effects in already established form of NO-deficient hypertension
- Simultaneous administration of N-acetylcysteine prevented the development of NO-deficient hypertension in rats chronically treated with L-NAME (50 mg/kg/day). Lowering of oxygen radical production and/or their action on cell membranes was accompanied by partial restoration of NO synthase activity attenuated by chronic L-NAME treatment. N-acetylcysteine has better preventive than therapeutic effects, because it has only minimal effects in already established form of NO-deficient hypertension (en)
- Současné podávání N-acetylcysteinu zablokovalo rozvoj NO-deficientní hypertenze vyvolané u potkana chronickou aplikací L-NAME (50 mg/kg/den). Současně dochází k potlačení produkce kyslíkových radikálů resp. jejich působení na buněčné membrány a částečné obnově aktivity NO syntázy utlumené chronickým podáváním L-NAME. N-acetylcystein má lepší preventivní než terapeutické účinky, neboť nemá příliš velký účinek u již rozvinuté formy NO-deficientní hypertenze (cs)
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Title
| - Chronic N-acetylcysteine administration prevents development of hypertension in Nomega-nitro-L-arginine methyl ester-treated rats: the role of reactive oxygen species
- Chronické podávání N-acetylcysteinu zabrání rozvoji L-NAME hypertenze u potkana: úloha reaktivních kyslíkových radikálů (cs)
- Chronic N-acetylcysteine administration prevents development of hypertension in Nomega-nitro-L-arginine methyl ester-treated rats: the role of reactive oxygen species (en)
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skos:prefLabel
| - Chronic N-acetylcysteine administration prevents development of hypertension in Nomega-nitro-L-arginine methyl ester-treated rats: the role of reactive oxygen species
- Chronické podávání N-acetylcysteinu zabrání rozvoji L-NAME hypertenze u potkana: úloha reaktivních kyslíkových radikálů (cs)
- Chronic N-acetylcysteine administration prevents development of hypertension in Nomega-nitro-L-arginine methyl ester-treated rats: the role of reactive oxygen species (en)
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skos:notation
| - RIV/67985823:_____/05:00020889!RIV06-AV0-67985823
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA305/03/0769), P(NR7786), Z(AV0Z5011922)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/67985823:_____/05:00020889
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - N-acetylcysteine; nitric oxide synthase; superoxide anions (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kuneš, Jaroslav
- Zicha, Josef
- Rauchová, Hana
- Vokurková, Martina
- Dobešová, Zdenka
- Pecháňová, O.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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is http://linked.open...avai/riv/vysledek
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