About: Age- and Sex-Dependent Effects of Ethanol on Hippocampal Hemicholinum-3 Sensitive Choline Carriers during Postnatal Development of Rats.     Goto   Sponge   NotDistinct   Permalink

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  • Vulnerability of hippocampal hemicholinium-3 (HC-3) sensitive carriers to ethanol was evaluated in vitro during rat postnatal development. The high-affinity uptake of (3H)choline (HACU) and the specific binding of (3H)HC-3 were measured in 7-, 14-, 60-day and 3-month old male and female rats. Both age- and sex-dependent alterations in basal HACU mediated by alcohol were observed in the immature tissue. Our results suggest the noncompetitive binding of alcohol to choline carriers from immature male tissue.
  • Vulnerability of hippocampal hemicholinium-3 (HC-3) sensitive carriers to ethanol was evaluated in vitro during rat postnatal development. The high-affinity uptake of (3H)choline (HACU) and the specific binding of (3H)HC-3 were measured in 7-, 14-, 60-day and 3-month old male and female rats. Both age- and sex-dependent alterations in basal HACU mediated by alcohol were observed in the immature tissue. Our results suggest the noncompetitive binding of alcohol to choline carriers from immature male tissue. (en)
Title
  • Age- and Sex-Dependent Effects of Ethanol on Hippocampal Hemicholinum-3 Sensitive Choline Carriers during Postnatal Development of Rats.
  • Age- and Sex-Dependent Effects of Ethanol on Hippocampal Hemicholinum-3 Sensitive Choline Carriers during Postnatal Development of Rats. (en)
skos:prefLabel
  • Age- and Sex-Dependent Effects of Ethanol on Hippocampal Hemicholinum-3 Sensitive Choline Carriers during Postnatal Development of Rats.
  • Age- and Sex-Dependent Effects of Ethanol on Hippocampal Hemicholinum-3 Sensitive Choline Carriers during Postnatal Development of Rats. (en)
skos:notation
  • RIV/67985807:_____/03:06030031!RIV/2004/AV0/A06004/N
http://linked.open.../vavai/riv/strany
  • 397;405
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z1030915)
http://linked.open...iv/cisloPeriodika
  • 3/4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 597602
http://linked.open...ai/riv/idVysledku
  • RIV/67985807:_____/03:06030031
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • ethanol; high-affinity transport; hemicholinium-3; postnatal development; hippocampus (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [4C417EB1881D]
http://linked.open...i/riv/nazevZdroje
  • Neurochemical Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 28
http://linked.open...iv/tvurceVysledku
  • Klaschka, Jan
  • Krištofiková, Z.
  • Platilová, V.
http://linked.open...n/vavai/riv/zamer
issn
  • 0364-3190
number of pages
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