About: Preparation and Biological Properties of Ring-Substituted 3-Hydroxynaphthalene-2-carboxanilides     Goto   Sponge   NotDistinct   Permalink

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Description
  • In this study a series of twenty-five ring-substituted 3-hydroxy-N-phenylnaphthalene-2-carboxanilides were prepared. The procedures for synthesis of the compounds are presented. The compounds were tested for their activity related to inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary in vitro screening of the synthesized compounds was also performed against four Staphylococcus strains. Several compounds showed noteworthy biological activity especially against methicillin-resistant Staphylococcus aureus strains. For all the compounds structure-activity relationships (SAR) are discussed.
  • In this study a series of twenty-five ring-substituted 3-hydroxy-N-phenylnaphthalene-2-carboxanilides were prepared. The procedures for synthesis of the compounds are presented. The compounds were tested for their activity related to inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary in vitro screening of the synthesized compounds was also performed against four Staphylococcus strains. Several compounds showed noteworthy biological activity especially against methicillin-resistant Staphylococcus aureus strains. For all the compounds structure-activity relationships (SAR) are discussed. (en)
Title
  • Preparation and Biological Properties of Ring-Substituted 3-Hydroxynaphthalene-2-carboxanilides
  • Preparation and Biological Properties of Ring-Substituted 3-Hydroxynaphthalene-2-carboxanilides (en)
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  • Preparation and Biological Properties of Ring-Substituted 3-Hydroxynaphthalene-2-carboxanilides
  • Preparation and Biological Properties of Ring-Substituted 3-Hydroxynaphthalene-2-carboxanilides (en)
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  • RIV/67179843:_____/13:00382617!RIV14-MSM-67179843
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  • I, P(ED1.1.00/02.0073)
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  • 98939
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  • RIV/67179843:_____/13:00382617
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  • Naphthalene-2-carboxanilides; PET inhibition; Spinach chloroplasts; Staphylococcus aureus; Structure-activity relationships (en)
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  • [97E52309E94C]
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  • Proceedings of the 16th International Electronic Conference on Synthetic Organic Chemistry
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  • Jampílek, J.
  • Oravec, Michal
  • Kos, J.
  • Bobál, P.
  • Gonec, T.
  • Králová, K.
  • Pavlica, J.
  • Pesko, M.
  • Zadražilová, I.
  • Čížek, A.
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  • MDPI
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  • 3-906980-26-X
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