About: Why to use propensity score in observational studies? Case study based on data from the Czech clinical database AHEAD 2006-09

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About: Why to use propensity score in observational studies? Case study based on data from the Czech clinical database AHEAD 2006-09 Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1016/j.crvasa.2013.04.001
Description	Randomized clinical trials represent the gold standard of the evidence based medicine research; nevertheless they may not always be feasible or ethical and the researchers have to rely on observational studies or research databases. However, obtaining reliable results from these studies requires the elimination of potential influence of confounding factors. Fortunately, several statistical methods capable of identifying and reducing the impact of confounding factors exist. One of them is the propensity score which has been frequently used in recent times to estimate relevant clinical effects adjusted for given confounders. This work aims to provide a concise and practical guide to propensity scores by means of an easily understandable case study. The case study is focused on gender differences in mortality rates of patients with acute heart failure in the Czech research database AHEAD (Acute Heart Failure Database). Randomized clinical trials represent the gold standard of the evidence based medicine research; nevertheless they may not always be feasible or ethical and the researchers have to rely on observational studies or research databases. However, obtaining reliable results from these studies requires the elimination of potential influence of confounding factors. Fortunately, several statistical methods capable of identifying and reducing the impact of confounding factors exist. One of them is the propensity score which has been frequently used in recent times to estimate relevant clinical effects adjusted for given confounders. This work aims to provide a concise and practical guide to propensity scores by means of an easily understandable case study. The case study is focused on gender differences in mortality rates of patients with acute heart failure in the Czech research database AHEAD (Acute Heart Failure Database). (en)
Title	Why to use propensity score in observational studies? Case study based on data from the Czech clinical database AHEAD 2006-09 Why to use propensity score in observational studies? Case study based on data from the Czech clinical database AHEAD 2006-09 (en)
skos:prefLabel	Why to use propensity score in observational studies? Case study based on data from the Czech clinical database AHEAD 2006-09 Why to use propensity score in observational studies? Case study based on data from the Czech clinical database AHEAD 2006-09 (en)
skos:notation	RIV/65269705:_____/13:#0002172!RIV14-MZ0-65269705
http://linked.open...avai/predkladatel	Fakultní nemocnice Brno
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(ED1.100/02/0123), P(GD102/09/H083), S
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Pařenica, Jiří Špinar, Jindřich
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Brno / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	117362
http://linked.open...ai/riv/idVysledku	RIV/65269705:_____/13:#0002172
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Acute heart failure; AHEAD; Mortality; Propensity score (en)
http://linked.open.../riv/klicoveSlovo	AHEAD Acute heart failure Propensity score Mortality
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[96B9C182DF4A]
http://linked.open...i/riv/nazevZdroje	Cor et Vasa
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Information Technology in Biomedical Engineering St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	55
http://linked.open...iv/tvurceVysledku	Pařenica, Jiří Špinar, Jindřich
issn	1803-7712
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.crvasa.2013.04.001

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