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Description
  • Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known. METHODS: We conducted a randomized, double-blind, double-dummy trial comparing two once-daily regimens of edoxaban with warfarin in 21,105 patients with moderate-to-high-risk atrial fibrillation (median follow-up, 2.8 years). The primary efficacy end point was stroke or systemic embolism. Each edoxaban regimen was tested for noninferiority to warfarin during the treatment period.
  • Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known. METHODS: We conducted a randomized, double-blind, double-dummy trial comparing two once-daily regimens of edoxaban with warfarin in 21,105 patients with moderate-to-high-risk atrial fibrillation (median follow-up, 2.8 years). The primary efficacy end point was stroke or systemic embolism. Each edoxaban regimen was tested for noninferiority to warfarin during the treatment period. (en)
Title
  • Edoxaban versus warfarin in patients with atrial fibrillation
  • Edoxaban versus warfarin in patients with atrial fibrillation (en)
skos:prefLabel
  • Edoxaban versus warfarin in patients with atrial fibrillation
  • Edoxaban versus warfarin in patients with atrial fibrillation (en)
skos:notation
  • RIV/65269705:_____/13:#0002103!RIV14-MZ0-65269705
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 22
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 71228
http://linked.open...ai/riv/idVysledku
  • RIV/65269705:_____/13:#0002103
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Edoxaban; Warfarin; Atrial Fibrillation (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [68416383EA14]
http://linked.open...i/riv/nazevZdroje
  • Edoxaban versus warfarin in patients with atrial fibrillation
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 369
http://linked.open...iv/tvurceVysledku
  • Špinar, Jindřich
http://linked.open...ain/vavai/riv/wos
  • 000327467500007
issn
  • 0028-4793
number of pages
http://bibframe.org/vocab/doi
  • 10.1056/NEJMoa1310907
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