About: 1q21 amplification with additional genetic abnormalities but not isolated 1q21 gain is a negative prognostic factor in newly diagnosed patients with multiple myeloma treated with thalidomide-based regimens     Goto   Sponge   NotDistinct   Permalink

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  • In this study we assessed the prognostic value of amp(1q21) alone and in combination with del(17p13), del(13q14) and t(4,14)(p16;q32) detected by fl uorescence in situ hybridization(FISH) in newly diagnosed patients with MM treated with thalidomide-based induction regimens. Th e primary endpoints were response rate after fi rst-line therapy, PFS and OS.
  • In this study we assessed the prognostic value of amp(1q21) alone and in combination with del(17p13), del(13q14) and t(4,14)(p16;q32) detected by fl uorescence in situ hybridization(FISH) in newly diagnosed patients with MM treated with thalidomide-based induction regimens. Th e primary endpoints were response rate after fi rst-line therapy, PFS and OS. (en)
Title
  • 1q21 amplification with additional genetic abnormalities but not isolated 1q21 gain is a negative prognostic factor in newly diagnosed patients with multiple myeloma treated with thalidomide-based regimens
  • 1q21 amplification with additional genetic abnormalities but not isolated 1q21 gain is a negative prognostic factor in newly diagnosed patients with multiple myeloma treated with thalidomide-based regimens (en)
skos:prefLabel
  • 1q21 amplification with additional genetic abnormalities but not isolated 1q21 gain is a negative prognostic factor in newly diagnosed patients with multiple myeloma treated with thalidomide-based regimens
  • 1q21 amplification with additional genetic abnormalities but not isolated 1q21 gain is a negative prognostic factor in newly diagnosed patients with multiple myeloma treated with thalidomide-based regimens (en)
skos:notation
  • RIV/65269705:_____/12:#0001962!RIV13-MZ0-65269705
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
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  • I
http://linked.open...iv/cisloPeriodika
  • 12
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http://linked.open...aciTvurceVysledku
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  • 183229
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  • RIV/65269705:_____/12:#0001962
http://linked.open...riv/jazykVysledku
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  • multiple myeloma (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [3B55C46388EC]
http://linked.open...i/riv/nazevZdroje
  • Leukemia & Lymphoma
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  • 53
http://linked.open...iv/tvurceVysledku
  • Hájek, Roman
  • Grzasko, Norbert
http://linked.open...ain/vavai/riv/wos
  • 000310709000030
issn
  • 1042-8194
number of pages
http://bibframe.org/vocab/doi
  • 10.3109/10428194.2012.684349
is http://linked.open...avai/riv/vysledek of
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