About: Proteomic analysis in multiple myeloma research

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Multiple myeloma (MM) is an incurable plasma cell (PC) malignancy characterized by the accumulation of monoclonal PCs in the bone marrow. For deeper understanding of the molecular mechanisms involved in the development of this disease, the influence of microenvironment, or the prediction of response of tumor PCs to anti-MM treatment, it is possible to use modern technologies for genomic and proteomic analyses. Due to progress in instrumentation, one of the main tools of proteomic analysis is mass spectrometry in combination with chosen separation techniques. This review will provide a short survey of the most commonly used proteomic techniques and show examples of their applications in MM proteome studies. Multiple myeloma (MM) is an incurable plasma cell (PC) malignancy characterized by the accumulation of monoclonal PCs in the bone marrow. For deeper understanding of the molecular mechanisms involved in the development of this disease, the influence of microenvironment, or the prediction of response of tumor PCs to anti-MM treatment, it is possible to use modern technologies for genomic and proteomic analyses. Due to progress in instrumentation, one of the main tools of proteomic analysis is mass spectrometry in combination with chosen separation techniques. This review will provide a short survey of the most commonly used proteomic techniques and show examples of their applications in MM proteome studies. (en)
Title	Proteomic analysis in multiple myeloma research Proteomic analysis in multiple myeloma research (en)
skos:prefLabel	Proteomic analysis in multiple myeloma research Proteomic analysis in multiple myeloma research (en)
skos:notation	RIV/65269705:_____/11:#0001280!RIV12-MZ0-65269705
http://linked.open...avai/predkladatel	Fakultní nemocnice Brno
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(LC06027), P(NS9683), Z(MSM0021622415), Z(MSM0021622434)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Hájek, Roman
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Brno / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	224825
http://linked.open...ai/riv/idVysledku	RIV/65269705:_____/11:#0001280
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	multiple myeloma (en)
http://linked.open.../riv/klicoveSlovo	multiple myeloma
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[5CFACD1444E4]
http://linked.open...i/riv/nazevZdroje	Molecular Biotechnology
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	University Research Centre - Czech Myeloma Group Alterations of genome and proteome in leukemic patients with Graft-versus-Host disease
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	47
http://linked.open...iv/tvurceVysledku	Hájek, Roman Čumová, Jana
http://linked.open...ain/vavai/riv/wos	000285472500010
http://linked.open...n/vavai/riv/zamer	Molecular basis of cell and tissue regulations From classic prognostic markers to clinical applications in selected pharmacogenomic and pharmacoproteomic projects in multiple myeloma and monoclonal gammapathies
issn	1073-6085
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s12033-010-9326-x
is http://linked.open...avai/riv/vysledek of	Proteomic analysis in multiple myeloma research Proteomic analysis in multiple myeloma research

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