About: microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We performed miRNAs profiling in a population of regulatory T celss (Tregs) separated from peripheral blood of five type 1 diabetic patients and six healthy donors. For more detailed molecular char- acterisation of Tregs, we additionally compared miRNAs expression profiles of Tregs and conventional T cells. Tregs were isolated according to CD3+, CD4+, CD25hi+ and CD127low by flow cytometry, and miRNA expression profiling was performed using TaqMan Array Human MicroRNA Panel-1 (384-well low density array). This is the first study demonstrating changes in miRNA expression profiles occurring in Tregs of T1D patients and a miRNAs signature of adult Tregs. We performed miRNAs profiling in a population of regulatory T celss (Tregs) separated from peripheral blood of five type 1 diabetic patients and six healthy donors. For more detailed molecular char- acterisation of Tregs, we additionally compared miRNAs expression profiles of Tregs and conventional T cells. Tregs were isolated according to CD3+, CD4+, CD25hi+ and CD127low by flow cytometry, and miRNA expression profiling was performed using TaqMan Array Human MicroRNA Panel-1 (384-well low density array). This is the first study demonstrating changes in miRNA expression profiles occurring in Tregs of T1D patients and a miRNAs signature of adult Tregs. (en)
Title	microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients (en)
skos:prefLabel	microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients (en)
skos:notation	RIV/65269705:_____/10:#0001086!RIV11-MZ0-65269705
http://linked.open...avai/riv/aktivita	P V
http://linked.open...avai/riv/aktivity	P(2B08066), P(NR9355), V
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Michálek, Jaroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Brno / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	271244
http://linked.open...ai/riv/idVysledku	RIV/65269705:_____/10:#0001086
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	microRNA (en)
http://linked.open.../riv/klicoveSlovo	microRNA
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[87B956D29878]
http://linked.open...i/riv/nazevZdroje	Cellular Immunology
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Immunoregulatory functions in children with diabetes mellitus Novel treatment of genetically determined metabolic disease, type 1 diabetes, using an immunotherapeutical approach.
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	260
http://linked.open...iv/tvurceVysledku	Michálek, Jaroslav Slabý, Ondřej
http://linked.open...ain/vavai/riv/wos	000273594200003
issn	0008-8749
number of pages	5 (xsd:int)
is http://linked.open...avai/riv/vysledek of	microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients

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