About: Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results

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About: Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Injection of botulinum toxin (BT) and pneumatic dilatation are available methods in nonsurgical treatment of achalasia. Authors anticipate beneficial effect of prior BT injection on the success of pneumatic dilatation and duration of its effect. There are no long-term data available to assess efficacy of combined treatment.Result of prospective study on 51 consecutive patients treated by comination method are presented. The cumulative 5 years remission rate in combined treated patients 69% was higher than in controls 50%; however it, was not statistically significant (P = 0.07). Eight patients (17%) with relapse of dysphagia were referred to laparoscopic Heller myotomy with no surgical complication.Initial injection of BT followed by PD seems to be effective for long-term results with fewer complications. But the combined therapy is not significantly superior to PD alone. Injection of botulinum toxin (BT) and pneumatic dilatation are available methods in nonsurgical treatment of achalasia. Authors anticipate beneficial effect of prior BT injection on the success of pneumatic dilatation and duration of its effect. There are no long-term data available to assess efficacy of combined treatment.Result of prospective study on 51 consecutive patients treated by comination method are presented. The cumulative 5 years remission rate in combined treated patients 69% was higher than in controls 50%; however it, was not statistically significant (P = 0.07). Eight patients (17%) with relapse of dysphagia were referred to laparoscopic Heller myotomy with no surgical complication.Initial injection of BT followed by PD seems to be effective for long-term results with fewer complications. But the combined therapy is not significantly superior to PD alone. (en)
Title	Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results (en)
skos:prefLabel	Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results (en)
skos:notation	RIV/65269705:_____/10:#0001040!RIV11-MZ0-65269705
http://linked.open...avai/riv/aktivita	P V
http://linked.open...avai/riv/aktivity	P(2B06060), V
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Novotný, Ivo Dolina, J. Hep, Aleš Sedmík, Jaroslav Prokešová, Jitka Válek, Vlastimil Kroupa, Radek Mrázová, Jolanta
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Brno / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	251227
http://linked.open...ai/riv/idVysledku	RIV/65269705:_____/10:#0001040
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	achalasia (en)
http://linked.open.../riv/klicoveSlovo	achalasia
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[C34333548C67]
http://linked.open...i/riv/nazevZdroje	Diseases of the Esophagus
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Increasing the efficacy of the diagnostics and treatment of gastro-esophageal reflux disease.
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	23
http://linked.open...iv/tvurceVysledku	Novotný, Ivo Válek, Vlastimil Hep, Aleš Kroupa, Radek Dolina, Jiří Sedmík, Jaroslav Prokešová, Jitka Mrázová, Jolanta
http://linked.open...ain/vavai/riv/wos	000274622100003
issn	1120-8694
number of pages	6 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results

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