About: Rapid Screening of Permeation of Rutin through Skin Using Alaptide Enantiomers     Goto   Sponge   NotDistinct   Permalink

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Description
  • The investigation deals with the influence of permeation of rutin from carboxymethyl cellulose gel through full-thickness pig ear skin by (S)- and (R)-alaptide as potential excipients. Alaptide, 8-methyl-6,9-diazaspiro[4.5]decan-7,10-dione, is the original Czech compound. By means of this rapid screening it was found out that the permeation of rutin through the skin increased linearly with time and was enhanced by both enantiomers of alaptide: approx. 1.2-fold by (R)-alaptide and approx. 1.5-fold by (S)-alaptide
  • The investigation deals with the influence of permeation of rutin from carboxymethyl cellulose gel through full-thickness pig ear skin by (S)- and (R)-alaptide as potential excipients. Alaptide, 8-methyl-6,9-diazaspiro[4.5]decan-7,10-dione, is the original Czech compound. By means of this rapid screening it was found out that the permeation of rutin through the skin increased linearly with time and was enhanced by both enantiomers of alaptide: approx. 1.2-fold by (R)-alaptide and approx. 1.5-fold by (S)-alaptide (en)
Title
  • Rapid Screening of Permeation of Rutin through Skin Using Alaptide Enantiomers
  • Rapid Screening of Permeation of Rutin through Skin Using Alaptide Enantiomers (en)
skos:prefLabel
  • Rapid Screening of Permeation of Rutin through Skin Using Alaptide Enantiomers
  • Rapid Screening of Permeation of Rutin through Skin Using Alaptide Enantiomers (en)
skos:notation
  • RIV/62157124:16370/14:43873204!RIV15-MSM-16370___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • O
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  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 41364
http://linked.open...ai/riv/idVysledku
  • RIV/62157124:16370/14:43873204
http://linked.open...riv/jazykVysledku
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  • Enantiomers; Alaptide; Rutin; Skin Permeation; Screening (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • HR - Chorvatská republika
http://linked.open...ontrolniKodProRIV
  • [7D8D8A36990F]
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  • ADMET & DMPK
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  • 2
http://linked.open...iv/tvurceVysledku
  • Jampílek, Josef
  • Opatřilová, Radka
  • Bobáľ, Pavel
  • Černíková, Aneta
issn
  • 1848-7718
number of pages
http://bibframe.org/vocab/doi
  • 10.5599/admet.2.4.155
http://localhost/t...ganizacniJednotka
  • 16370
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