About: Synthesis and photosynthetic electron transport inhibition of 2-substituted 6-fluorobenzothiazoles     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • Series of ten N-substituted 2-(aminoethyl)-6-fluorobenzothiazoles inhibited photosynthetic electron transport in spinach chloroplasts. The inhibitory activity linearly increased with hydrophobic contributions (expressed as hydrophobic constants pi) and molar volumes of individual substituents in C-(2) position of 6-fluorobenzothiazole scaffold to the optima pi ca. 2 and MV ca. 233 cm(3), while for more lipophilic and/or bulkier derivatives PET inhibiting activity linearly decreased. The site of inhibitory action of the tested compounds is situated on the donor side of photosystem II, and interaction of these compounds with aromatic amino acid residues in photosynthetic proteins was confirmed by fluorescence spectroscopy. Synthesis and characterization of five new N alpha-(alkoxycarbonyl)-N-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-l-phenylalaninamides is presented as well.
  • Series of ten N-substituted 2-(aminoethyl)-6-fluorobenzothiazoles inhibited photosynthetic electron transport in spinach chloroplasts. The inhibitory activity linearly increased with hydrophobic contributions (expressed as hydrophobic constants pi) and molar volumes of individual substituents in C-(2) position of 6-fluorobenzothiazole scaffold to the optima pi ca. 2 and MV ca. 233 cm(3), while for more lipophilic and/or bulkier derivatives PET inhibiting activity linearly decreased. The site of inhibitory action of the tested compounds is situated on the donor side of photosystem II, and interaction of these compounds with aromatic amino acid residues in photosynthetic proteins was confirmed by fluorescence spectroscopy. Synthesis and characterization of five new N alpha-(alkoxycarbonyl)-N-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-l-phenylalaninamides is presented as well. (en)
Title
  • Synthesis and photosynthetic electron transport inhibition of 2-substituted 6-fluorobenzothiazoles
  • Synthesis and photosynthetic electron transport inhibition of 2-substituted 6-fluorobenzothiazoles (en)
skos:prefLabel
  • Synthesis and photosynthetic electron transport inhibition of 2-substituted 6-fluorobenzothiazoles
  • Synthesis and photosynthetic electron transport inhibition of 2-substituted 6-fluorobenzothiazoles (en)
skos:notation
  • RIV/62157124:16370/14:43872711!RIV15-MSM-16370___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, V
http://linked.open...iv/cisloPeriodika
  • 11
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 48986
http://linked.open...ai/riv/idVysledku
  • RIV/62157124:16370/14:43872711
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Structure-activity relationships; Bioorganic chemistry; Herbicidal activity; Photosynthetic electron transport; Heterocycles (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • AT - Rakouská republika
http://linked.open...ontrolniKodProRIV
  • [C81A57C74208]
http://linked.open...i/riv/nazevZdroje
  • Monatshefte fur chemie
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 145
http://linked.open...iv/tvurceVysledku
  • Jampílek, Josef
  • Imramovský, Aleš
  • Kráľová, Katarína
  • Peško, Matúš
http://linked.open...ain/vavai/riv/wos
  • 000343882400013
issn
  • 0026-9247
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s00706-014-1283-9
http://localhost/t...ganizacniJednotka
  • 16370
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 47 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software