Attributes | Values |
---|
rdf:type
| |
Description
| - The pellets containing rutin prepared by extrusion/ spheronization method were coated with natrium alginate - chitosan film. Important quality parameters in pellets before the coating were determined, and after the coating dissolution profiles of the drug were evaluated in dissolution media of pH corresponding to the conditions in gastrointestinal tract. Samples of coated pellets were located in the boxes for stability testing under different conditions, i.e. 25 °C and 60 % of relative humidity (RH); 30 °C and 65 % RH and 40 °C and 75 % RH. After 1, 3, 6, 9 and 12 months (or 1, 3 and 6 months), dissolution test was repeated and compared with the original profiles using similarity factors. All similarity factor values above 50 indicate excellent stability of alginate-chitosan films.
- The pellets containing rutin prepared by extrusion/ spheronization method were coated with natrium alginate - chitosan film. Important quality parameters in pellets before the coating were determined, and after the coating dissolution profiles of the drug were evaluated in dissolution media of pH corresponding to the conditions in gastrointestinal tract. Samples of coated pellets were located in the boxes for stability testing under different conditions, i.e. 25 °C and 60 % of relative humidity (RH); 30 °C and 65 % RH and 40 °C and 75 % RH. After 1, 3, 6, 9 and 12 months (or 1, 3 and 6 months), dissolution test was repeated and compared with the original profiles using similarity factors. All similarity factor values above 50 indicate excellent stability of alginate-chitosan films. (en)
|
Title
| - Stability testing of alginate-chitosan films
- Stability testing of alginate-chitosan films (en)
|
skos:prefLabel
| - Stability testing of alginate-chitosan films
- Stability testing of alginate-chitosan films (en)
|
skos:notation
| - RIV/62157124:16370/12:43871091!RIV13-MSM-16370___
|
http://linked.open...avai/predkladatel
| |
http://linked.open...avai/riv/aktivita
| |
http://linked.open...avai/riv/aktivity
| |
http://linked.open...iv/cisloPeriodika
| |
http://linked.open...vai/riv/dodaniDat
| |
http://linked.open...aciTvurceVysledku
| |
http://linked.open.../riv/druhVysledku
| |
http://linked.open...iv/duvernostUdaju
| |
http://linked.open...titaPredkladatele
| |
http://linked.open...dnocenehoVysledku
| |
http://linked.open...ai/riv/idVysledku
| - RIV/62157124:16370/12:43871091
|
http://linked.open...riv/jazykVysledku
| |
http://linked.open.../riv/klicovaSlova
| - alginate, chitosan, films, colon drug delivery, stability (en)
|
http://linked.open.../riv/klicoveSlovo
| |
http://linked.open...odStatuVydavatele
| |
http://linked.open...ontrolniKodProRIV
| |
http://linked.open...i/riv/nazevZdroje
| - Česká a slovenská farmacie
|
http://linked.open...in/vavai/riv/obor
| |
http://linked.open...ichTvurcuVysledku
| |
http://linked.open...cetTvurcuVysledku
| |
http://linked.open...UplatneniVysledku
| |
http://linked.open...v/svazekPeriodika
| |
http://linked.open...iv/tvurceVysledku
| - Dvořáčková, Kateřina
- Rabišková, Miloslava
- Kofroňová, Lenka
|
issn
| |
number of pages
| |
http://localhost/t...ganizacniJednotka
| |
is http://linked.open...avai/riv/vysledek
of | |