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Description
| - Pro dibazické alkylestery 2- a 3-alkoxyfenylkarbamové kyseliny byly stanoveny základní fyzikálno-chemické parametry ? rozpustnost, disociační konstanta, rozdělovací koeficient, RM hodnoty z chromatografie na tenké vrstvě využívající obrácených fází a retenční faktor z HPLC. Experimentální hodnoty (rozpustnost, pKa, log P) byly následně korelovány s vypočtenými hodnotami s využitím programů pracujících na metodách tzv. asociovaných neuronových sítí , atom-aditivních a fragmentových přístupů. (cs)
- The basic physicochemical properties, acidity and lipophilicity parameters of dibasic ester of 2- and 3-alkyloxy substituted phenylcarbamic acids were estimated (solubility, dissociation constant, logarithm of partition coefficient, RM value obtained by reversed-phase thin-layer choromatography and retention factor from HPLC). For the analyzed set of compounds the experimentally obtained data (solubility, pKa, log P) were completely correlated with those computed using various program packages based on the associative artificial neural network (ASNN), atomadditive and fragmental methods.
- The basic physicochemical properties, acidity and lipophilicity parameters of dibasic ester of 2- and 3-alkyloxy substituted phenylcarbamic acids were estimated (solubility, dissociation constant, logarithm of partition coefficient, RM value obtained by reversed-phase thin-layer choromatography and retention factor from HPLC). For the analyzed set of compounds the experimentally obtained data (solubility, pKa, log P) were completely correlated with those computed using various program packages based on the associative artificial neural network (ASNN), atomadditive and fragmental methods. (en)
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Title
| - The physicochemical properties of dibasic alkylesters of 2- and 3-alkoxysubstituted phenylcarbamic acid
- The physicochemical properties of dibasic alkylesters of 2- and 3-alkoxysubstituted phenylcarbamic acid (en)
- Fyzikálně-chemické vlastnosti dibazických alkylesterů 2- a 3-alkoxy substituovaných derivátů kyseliny fenylkarbamové (cs)
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skos:prefLabel
| - The physicochemical properties of dibasic alkylesters of 2- and 3-alkoxysubstituted phenylcarbamic acid
- The physicochemical properties of dibasic alkylesters of 2- and 3-alkoxysubstituted phenylcarbamic acid (en)
- Fyzikálně-chemické vlastnosti dibazických alkylesterů 2- a 3-alkoxy substituovaných derivátů kyseliny fenylkarbamové (cs)
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skos:notation
| - RIV/62157124:16370/07:00001110!RIV08-MSM-16370___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/62157124:16370/07:00001110
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - local anaesthetics; phenylcarbamates; acidity; lipophilicity (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Acta Facultatis Pharmaceuticae Universitatis Comenianae Bratislava
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Andriamainty, Fils
- Csöllei, Jozef
- Malík, Ivan
- Sedlárová, Eva
- Čižmárik, Jozef
- Kečkéšová, Simona
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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