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| Description
| - Juvenile zebrafish (aged 20 days post hatching) were exposed for 20 days to three different batches of feed containing 500, 1000 and 2000 mg/kg of the commonly used preservative propylparaben (PP), respectively. After the exposure, the zebrafish were killed and the concentrations of the estrogen-dependent protein vitellogenin in their whole-body homogenates were measured by ELISA. The results obtained were compared with vitellogenin concentrations in control fish that received feed with no added propylparaben during the test and in fish from the positive control group receiving a diet containing 20 mg/kg natural estrogen, 17β-estradiol (E-2). The median vitellogenin concentrations in whole-body homogenates were 854 ng/ml (control group), 798, 829 and 810 ng/ml (fish exposed to 500; 1000 and 2000 mg/kg of PP respectively) and 1178 μg/ml (fish exposed to E-2). Since the exposure to the diet containing PP did not elicit significant induction of vitellogenin synthesis compared to control in any
- Juvenile zebrafish (aged 20 days post hatching) were exposed for 20 days to three different batches of feed containing 500, 1000 and 2000 mg/kg of the commonly used preservative propylparaben (PP), respectively. After the exposure, the zebrafish were killed and the concentrations of the estrogen-dependent protein vitellogenin in their whole-body homogenates were measured by ELISA. The results obtained were compared with vitellogenin concentrations in control fish that received feed with no added propylparaben during the test and in fish from the positive control group receiving a diet containing 20 mg/kg natural estrogen, 17β-estradiol (E-2). The median vitellogenin concentrations in whole-body homogenates were 854 ng/ml (control group), 798, 829 and 810 ng/ml (fish exposed to 500; 1000 and 2000 mg/kg of PP respectively) and 1178 μg/ml (fish exposed to E-2). Since the exposure to the diet containing PP did not elicit significant induction of vitellogenin synthesis compared to control in any (en)
- Juvenilní dania pruhovaná ve věku 20 dní po vylíhnutí byla po dobu 20 dnů exponována propylparabenem (PP) obsaženém v krmivu v koncentracích 500; 1000 resp. 2000 mg/kg. Po ukončení expozice byla dania utracena a v homogenátech jejích těl byly měřeny koncentrace vitellogeninu, jehož syntéza je řízena (xeno)estrogeny. Výsledky byly srovnány s kontrolní skupinou a se skupinou pozitivní kontroly přijímající krmivo obsahující 20 mg/kg přirozeného estrogenu 17β-estradiolu. Mediány koncentrací vitellogeninu v jednotlivých skupinách byly následující: 854 ng/ml v kontrolní skupině, 798; 829 and 810 ng/ml ve skupinách exponovaných 500; 1000 resp. 2000 mg/kg propylparabenu a 1178 μg/ml ve skupině exponované 17β-estradiolem. Vzhledem k tomu, že expozice ryb propylparabenem nevyvolala signifikantní indukci syntézy vitellogeninu, nebyl prokázán xenoestrogenní účinek testované látky. Na druhou stranu, v našem testu byl potvrzen estrogenní efekt 17β-estradiolu. (cs)
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| Title
| - The influence of propylparaben on vitellogenin production in juvenilie zebrafish (Danio rerio).
- The influence of propylparaben on vitellogenin production in juvenilie zebrafish (Danio rerio). (en)
- Vliv propylparabenu na produkci vitellogeninu u juvenilního dania pruhovaného /Danio rerio/. (cs)
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| skos:prefLabel
| - The influence of propylparaben on vitellogenin production in juvenilie zebrafish (Danio rerio).
- The influence of propylparaben on vitellogenin production in juvenilie zebrafish (Danio rerio). (en)
- Vliv propylparabenu na produkci vitellogeninu u juvenilního dania pruhovaného /Danio rerio/. (cs)
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| skos:notation
| - RIV/62157124:16270/07:00001238!RIV08-MSM-16270___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/62157124:16270/07:00001238
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - preservatives; parabens; xenoestrogens; vitellogenesis; fish (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/mistoVydani
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| http://linked.open...i/riv/nazevZdroje
| - Book of Abstracts - 6th International conference of Ph. D. students
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Svobodová, Zdeňka
- Dobšíková, Radka
- Mikula, Přemysl
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| http://linked.open...n/vavai/riv/zamer
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| number of pages
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| http://purl.org/ne...btex#hasPublisher
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| https://schema.org/isbn
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| http://localhost/t...ganizacniJednotka
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| is http://linked.open...avai/riv/vysledek
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