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| Description
| - Bromované zpomalovače hoření (BFRs) jsou organické látky používané v mnoha odvětvích průmyslu. Nejdůležitější skupinou BFRs jsou polybromované difenylétery (PBDEs), které z důvodu své persistence v životním prostředí, akumulace v potravních řetězcích a toxických účinků představují potenciální nebezpečí ohrožení zdraví zvířat a člověka. Polybromované difenylétery vykazují schopnost narušení procesů hormonální regulace v živých organismech snižováním koncentrací thyroxinu v plasmě exponovaných jedinců. In vitro studie prokázaly schopnost vazby těchto látek na estrogenní či androgenní receptory. V pokusech na hlodavcích byla zjištěna také neurotoxicita některých PBDEs. Přestože je používání PBDEs v průmyslu v současnosti do značné míry regulováno, výskyt těchto látek již byl zaznamenán také v oblastech bez zjevného průmyslového zatížení např. v Grónsku. Předkládaný článek shrnuje poznatky týkající se problematiky BFRs se zaměřením na PBDEs, popisuje toxické účinky těchto látek a jejich metabolismus v živ (cs)
- Brominated flame retardants (BFRs) are organic substances frequently used in many industries. The most important group within BFRs are polybrominated diphenyl ethers (PBDEs). Because they persist in the environment, get accumulated in food chains and have toxic effects, they are a potential health risk for both animals and man. Polybrominated diphenyl ethers may disrupt processes of hormonal regulation in living organisms by reducing thyroxine concentrations in the plasma of exposed individuals. In vitro studies have demonstrated the ability of these substances to bind to estrogen and androgen receptors. Tests on rodents have also demonstrated neurotoxicity of some of the PBDEs. Although industrial use of PBDEs is now regulated to a large extent, PBDEs have already been detected in areas with no apparent industrial load, e.g. in Greenland. This article presents an overview of BFRs-related issues with a particular emphasis on PBDEs, describes toxic effects of those substances and their metabolism in li
- Brominated flame retardants (BFRs) are organic substances frequently used in many industries. The most important group within BFRs are polybrominated diphenyl ethers (PBDEs). Because they persist in the environment, get accumulated in food chains and have toxic effects, they are a potential health risk for both animals and man. Polybrominated diphenyl ethers may disrupt processes of hormonal regulation in living organisms by reducing thyroxine concentrations in the plasma of exposed individuals. In vitro studies have demonstrated the ability of these substances to bind to estrogen and androgen receptors. Tests on rodents have also demonstrated neurotoxicity of some of the PBDEs. Although industrial use of PBDEs is now regulated to a large extent, PBDEs have already been detected in areas with no apparent industrial load, e.g. in Greenland. This article presents an overview of BFRs-related issues with a particular emphasis on PBDEs, describes toxic effects of those substances and their metabolism in li (en)
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| Title
| - Brominated flame retardants in the environment: their sources and effects (review).
- Brominated flame retardants in the environment: their sources and effects (review). (en)
- Bromované zpomalovače hoření: zdroje a účinky - review. (cs)
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| skos:prefLabel
| - Brominated flame retardants in the environment: their sources and effects (review).
- Brominated flame retardants in the environment: their sources and effects (review). (en)
- Bromované zpomalovače hoření: zdroje a účinky - review. (cs)
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| skos:notation
| - RIV/62157124:16270/06:00000967!RIV07-MSM-16270___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/62157124:16270/06:00000967
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - BFRs; polybrominated diphenyl ethers; tetrabromobisphenol A; environmental endocrine disruptors; toxicity; metabolism (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Svobodová, Zdeňka
- Mikula, Přemysl
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| http://linked.open...n/vavai/riv/zamer
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| http://localhost/t...ganizacniJednotka
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| is http://linked.open...avai/riv/vysledek
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