About: Differentiation Protocol for Hyaline-cartilage-producing Mesenchymal Stem Cells

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Recently, the ability of stem cells to differentiate into daughter tissues has become the focus of numerous experiments. After successfully using stem cells in experiments conducted in cardiology and neurology, there has been an increase in experimental studies examining the possible ways of exploiting stem cells in orthopaedics and traumatology. Stem cells capable of differentiating into hyaline cartilage can be derived not only from an embryonic stem cell; it is also possible to use mesenchymal stem cells (MSCs), which are found in the bone marrow. Following the isolation of MSCs and the stabilisation of a stem-cell colony, it is necessary to ?direct? the differentiation process towards chondrocytes. The procedure includes properly performed bone-marrow collection and isolation and the identification of a cell line of MSCs by means of CD marker expression. Among the subsequent steps are cell-line cultivation and, particularly, a correct differentiation protocol. In our experimental study, we preferr Recently, the ability of stem cells to differentiate into daughter tissues has become the focus of numerous experiments. After successfully using stem cells in experiments conducted in cardiology and neurology, there has been an increase in experimental studies examining the possible ways of exploiting stem cells in orthopaedics and traumatology. Stem cells capable of differentiating into hyaline cartilage can be derived not only from an embryonic stem cell; it is also possible to use mesenchymal stem cells (MSCs), which are found in the bone marrow. Following the isolation of MSCs and the stabilisation of a stem-cell colony, it is necessary to ?direct? the differentiation process towards chondrocytes. The procedure includes properly performed bone-marrow collection and isolation and the identification of a cell line of MSCs by means of CD marker expression. Among the subsequent steps are cell-line cultivation and, particularly, a correct differentiation protocol. In our experimental study, we preferr (en)
Title	Differentiation Protocol for Hyaline-cartilage-producing Mesenchymal Stem Cells Differentiation Protocol for Hyaline-cartilage-producing Mesenchymal Stem Cells (en)
skos:prefLabel	Differentiation Protocol for Hyaline-cartilage-producing Mesenchymal Stem Cells Differentiation Protocol for Hyaline-cartilage-producing Mesenchymal Stem Cells (en)
skos:notation	RIV/62157124:16170/10:00002584!RIV11-MZ0-16170___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(2B06130), P(NR9296)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Nečas, Alois
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Veterinární a farmaceutická univerzita Brno / Fakulta veterinárního lékařství
http://linked.open...dnocenehoVysledku	254390
http://linked.open...ai/riv/idVysledku	RIV/62157124:16170/10:00002584
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Mesenchymal stem cells; chondrogenesis; cartilage; differentiation; growth factor (en)
http://linked.open.../riv/klicoveSlovo	growth factor Mesenchymal stem cells cartilage differentiation chondrogenesis
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[A0E7A54F1127]
http://linked.open...i/riv/nazevZdroje	European Musculoskeletal Review
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	The use of the stem cells in growth plate injury treatment in pigs- experimantal study Synthesis of new biomaterials and preparation of stem cell derived cells, and their aplications in for the treatment of diseases affecting human tissues derived from mesoderm: cartilage, bone, ligament and meniscus.
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	4
http://linked.open...iv/tvurceVysledku	Klíma, Jiří Nečas, Alois Starý, David Křen, Leoš Gál, Petr Plánka, Ladislav Hlučilová, Jana
issn	1754-5072
number of pages	3 (xsd:int)
http://localhost/t...ganizacniJednotka	16170
is http://linked.open...avai/riv/vysledek of	Differentiation Protocol for Hyaline-cartilage-producing Mesenchymal Stem Cells Differentiation Protocol for Hyaline-cartilage-producing Mesenchymal Stem Cells Differentiation Protocol for Hyaline-cartilage-producing Mesenchymal Stem Cells

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