About: Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs.

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About: Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs. Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	This study appears from an experiment previously carried out in New Zealand white rabbits. Allogenic mesenchymal stem cells (MSCs) were transplanted into an iatrogenically-created defect in the lateral section of the distal physis of the left femur in 10 miniature pigs. The right femur with the same defect served as a control. To transfer MSCs, a freshly prepared porous scaffold was used, based on collagen and chitosan, constituting a compact tube into which MSCs were implanted. The pigs were euthanized four months after the transplantation. On average, the left femur with transplanted MSCs grew more in length (0.56-0.14 cm) compared with right femurs with physeal defect without transplanted MSCs (0.14-0.3 cm). The average angular (valgus) deformity of the left femur had an angle point of 0.78°, following measurement and X-ray examination, whereas in the right femur without transplantation it was 3.7°. The initial results indicate that preventive transplantation of MSCs into a physeal defect may preve This study appears from an experiment previously carried out in New Zealand white rabbits. Allogenic mesenchymal stem cells (MSCs) were transplanted into an iatrogenically-created defect in the lateral section of the distal physis of the left femur in 10 miniature pigs. The right femur with the same defect served as a control. To transfer MSCs, a freshly prepared porous scaffold was used, based on collagen and chitosan, constituting a compact tube into which MSCs were implanted. The pigs were euthanized four months after the transplantation. On average, the left femur with transplanted MSCs grew more in length (0.56-0.14 cm) compared with right femurs with physeal defect without transplanted MSCs (0.14-0.3 cm). The average angular (valgus) deformity of the left femur had an angle point of 0.78°, following measurement and X-ray examination, whereas in the right femur without transplantation it was 3.7°. The initial results indicate that preventive transplantation of MSCs into a physeal defect may preve (en)
Title	Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs. Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs. (en)
skos:prefLabel	Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs. Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs. (en)
skos:notation	RIV/62157124:16170/09:00002468!RIV10-MSM-16170___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(2B06130), P(NR8483), P(NR9296), Z(AV0Z50390703), Z(AV0Z50450515)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Srnec, Robert Raušer, Petr Nečas, Alois
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Veterinární a farmaceutická univerzita Brno / Fakulta veterinárního lékařství
http://linked.open...dnocenehoVysledku	347864
http://linked.open...ai/riv/idVysledku	RIV/62157124:16170/09:00002468
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Growth plate; Injury; Physis; Limb deformity; Mesenchymal stem cells (en)
http://linked.open.../riv/klicoveSlovo	Mesenchymal stem cells Physis Limb deformity Growth plate Injury
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[8A9CDCA3BC63]
http://linked.open...i/riv/nazevZdroje	Physiological Research
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	11 (xsd:int)
http://linked.open...vavai/riv/projekt	The use of the stem cells in growth plate injury treatment in pigs- experimantal study The use of the stem cells in growth plate injury treatment - experimental study Synthesis of new biomaterials and preparation of stem cell derived cells, and their aplications in for the treatment of diseases affecting human tissues derived from mesoderm: cartilage, bone, ligament and meniscus.
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	58
http://linked.open...iv/tvurceVysledku	Jančář, Josef Nečas, Alois Raušer, Petr Starý, David Filová, Eva Srnec, Robert Křen, Leoš Amler, Evžen Gál, Petr Plánka, Ladislav Hlučilová, Jana
http://linked.open...ain/vavai/riv/wos	000273296600013
http://linked.open...n/vavai/riv/zamer	New biotechnologies, nanomaterials and stem cells for use in regenerative medicine Genetic, functional and developmental potential of animal cells, tissues and organisms: their use in medicine, ecology and agriculture
issn	0862-8408
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	16170
is http://linked.open...avai/riv/vysledek of	Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs. Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs. Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs. Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs.

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