About: Comparison of Preventive and Therapeutic Transplantation of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs.

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About: Comparison of Preventive and Therapeutic Transplantation of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs. Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim of the study was to verify whether there is a difference in the lengthwise growth of the femurs and in their angular deformity when comparing preventive vs. therapeutic transplantation of allogeneic mesenchymal stem cells (MSCs) to an iatrogenic defect in the distal physis of femur. Modified composite chitosan/collagen type I scaffold with MSCs was transplanted to an iatrogenically created defect of the growth cartilage in the lateral condyle of the left femur in 20 miniature male pigs. In Group A of animals (n = 10) allogeneic MSCs were transplanted immediately after creating the defect in the distal physis of femur (preventive transplantation). In Group B of animals (n = 10) the same defect of the growth cartilage was treated by transplantation of allogeneic MSCs four weeks after its creation (therapeutic transplantation), after the excision of the bone bridge that had formed in it. On average, left femurs with a damaged distal physis and preventively transplanted allogeneic MSCs (Group A) The aim of the study was to verify whether there is a difference in the lengthwise growth of the femurs and in their angular deformity when comparing preventive vs. therapeutic transplantation of allogeneic mesenchymal stem cells (MSCs) to an iatrogenic defect in the distal physis of femur. Modified composite chitosan/collagen type I scaffold with MSCs was transplanted to an iatrogenically created defect of the growth cartilage in the lateral condyle of the left femur in 20 miniature male pigs. In Group A of animals (n = 10) allogeneic MSCs were transplanted immediately after creating the defect in the distal physis of femur (preventive transplantation). In Group B of animals (n = 10) the same defect of the growth cartilage was treated by transplantation of allogeneic MSCs four weeks after its creation (therapeutic transplantation), after the excision of the bone bridge that had formed in it. On average, left femurs with a damaged distal physis and preventively transplanted allogeneic MSCs (Group A) (en)
Title	Comparison of Preventive and Therapeutic Transplantation of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs. Comparison of Preventive and Therapeutic Transplantation of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs. (en)
skos:prefLabel	Comparison of Preventive and Therapeutic Transplantation of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs. Comparison of Preventive and Therapeutic Transplantation of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs. (en)
skos:notation	RIV/62157124:16170/09:00002467!RIV10-MSM-16170___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(2B06130), P(NR8483), P(NR9296), Z(AV0Z50450515)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Srnec, Robert Urbanová, Lucie Crha, Michal Nečas, Alois Dvořák, Milan Lorenzová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Veterinární a farmaceutická univerzita Brno / Fakulta veterinárního lékařství
http://linked.open...dnocenehoVysledku	307757
http://linked.open...ai/riv/idVysledku	RIV/62157124:16170/09:00002467
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	MSCs; growth plate; deformity; bone bridge (en)
http://linked.open.../riv/klicoveSlovo	bone bridge growth plate MSCs deformity
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[138FF6E6F465]
http://linked.open...i/riv/nazevZdroje	Acta veterinaria Brno
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	13 (xsd:int)
http://linked.open...vavai/riv/projekt	The use of the stem cells in growth plate injury treatment in pigs- experimantal study The use of the stem cells in growth plate injury treatment - experimental study Synthesis of new biomaterials and preparation of stem cell derived cells, and their aplications in for the treatment of diseases affecting human tissues derived from mesoderm: cartilage, bone, ligament and meniscus.
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	78
http://linked.open...iv/tvurceVysledku	Crha, Michal Dvořák, Milan Jančář, Josef Nečas, Alois Starý, David Urbanová, Lucie Srnec, Robert Křen, Leoš Gál, Petr Plánka, Ladislav Lorenzová, Jana Hlučilová, Jana Klíma, Josef
http://linked.open...ain/vavai/riv/wos	000267788000015
http://linked.open...n/vavai/riv/zamer	Genetic, functional and developmental potential of animal cells, tissues and organisms: their use in medicine, ecology and agriculture
issn	0001-7213
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	16170
is http://linked.open...avai/riv/vysledek of	Comparison of Preventive and Therapeutic Transplantation of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs. Comparison of Preventive and Therapeutic Transplantation of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs. Comparison of Preventive and Therapeutic Transplantation of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs. Comparison of Preventive and Therapeutic Transplantation of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs.

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