About: Mesenchymal Stem Cells in Bone Tissue Regeneration and Their Application in Bone Defect Healing

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	This synoptic study gives a concise overview of current knowledge of bone healing, the role of mesenchymal stem cells in bone tissue regeneration and contemporary possibilities of supporting regeneration of damaged bone. Attention of research concerning the healing of fractures with extensive loss of bone tissue following trauma, the treatment of belatedly healing or non-healing fractures or the healing of segmental bone defects following tumour resection, is focused on development of three-dimensional scaffolds planted with mesenchymal stem cells that might be used for reconstruction of such large bone lesions. Presented here are possibilities of transplantation of mesenchymal stem cells combined with biomaterials into bone defects, including the results of our own experimental studies dealing with the use of stem cells in the treatment of damaged tissues of the musculoskeletal system in animal models. This synoptic study gives a concise overview of current knowledge of bone healing, the role of mesenchymal stem cells in bone tissue regeneration and contemporary possibilities of supporting regeneration of damaged bone. Attention of research concerning the healing of fractures with extensive loss of bone tissue following trauma, the treatment of belatedly healing or non-healing fractures or the healing of segmental bone defects following tumour resection, is focused on development of three-dimensional scaffolds planted with mesenchymal stem cells that might be used for reconstruction of such large bone lesions. Presented here are possibilities of transplantation of mesenchymal stem cells combined with biomaterials into bone defects, including the results of our own experimental studies dealing with the use of stem cells in the treatment of damaged tissues of the musculoskeletal system in animal models. (en)
Title	Mesenchymal Stem Cells in Bone Tissue Regeneration and Their Application in Bone Defect Healing Mesenchymal Stem Cells in Bone Tissue Regeneration and Their Application in Bone Defect Healing (en)
skos:prefLabel	Mesenchymal Stem Cells in Bone Tissue Regeneration and Their Application in Bone Defect Healing Mesenchymal Stem Cells in Bone Tissue Regeneration and Their Application in Bone Defect Healing (en)
skos:notation	RIV/62157124:16170/09:00002466!RIV10-MSM-16170___
http://linked.open...avai/riv/aktivita	P V Z
http://linked.open...avai/riv/aktivity	P(2B06130), P(IAA500390702), V, Z(AV0Z50390703)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Srnec, Robert Raušer, Petr Urbanová, Lucie Crha, Michal Nečas, Alois Stehlík, Ladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Veterinární a farmaceutická univerzita Brno / Fakulta veterinárního lékařství
http://linked.open...dnocenehoVysledku	325522
http://linked.open...ai/riv/idVysledku	RIV/62157124:16170/09:00002466
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Tissue engineering; biomaterials; scaffold; segmental bone lesion; fracture healing; growth factors (en)
http://linked.open.../riv/klicoveSlovo	scaffold biomaterials Tissue engineering growth factors fracture healing segmental bone lesion
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[CAC277414300]
http://linked.open...i/riv/nazevZdroje	Acta veterinaria Brno
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Synthesis of new biomaterials and preparation of stem cell derived cells, and their aplications in for the treatment of diseases affecting human tissues derived from mesoderm: cartilage, bone, ligament and meniscus. Scaffolds from liposome nanofibers for tissue engineering
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	78
http://linked.open...iv/tvurceVysledku	Crha, Michal Jančář, Josef Nečas, Alois Raušer, Petr Urbanová, Lucie Srnec, Robert Amler, Evžen Stehlík, Ladislav Plánka, Ladislav Janovec, Jan
http://linked.open...ain/vavai/riv/wos	000273634200011
http://linked.open...n/vavai/riv/zamer	New biotechnologies, nanomaterials and stem cells for use in regenerative medicine
issn	0001-7213
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	16170
is http://linked.open...avai/riv/vysledek of	Mesenchymal Stem Cells in Bone Tissue Regeneration and Their Application in Bone Defect Healing Mesenchymal Stem Cells in Bone Tissue Regeneration and Their Application in Bone Defect Healing Mesenchymal Stem Cells in Bone Tissue Regeneration and Their Application in Bone Defect Healing Mesenchymal Stem Cells in Bone Tissue Regeneration and Their Application in Bone Defect Healing

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