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| rdf:type
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| Description
| - Laktoferin je glykoprotein náležící ke skupině nehemových železo vázajících monomerních glykoproteinů. Laktoferin ovlivňuje jak proliferaci, tak i diferenciaci imunitních buněk díky schopnosti modulovat buněčné signální cesty. V minulosti bylo všeobecně přijímáno, že psi produkují jen velmi omezené množství laktoferinu. V roce 2007 byl laktoferin vizualizován pomocí průtokové cytometrie v psích neutrofilech. Současně byl izolován z neutrofilů a byla prokázána jeho podobnost s humánním laktoferinem. Pyometra je závažné onemocnění postihující hlavně starší nuliparní feny v luteální fázi pohlavního cyklu aje spojena s neutrofílií a postižením některých imunitních funkcí, včetně aktivity lymfocytů. Tato inhibice byla vysvětlována vlivem celé řady faktorů včetně laktoferinu. Cílem této práce bylo změřit hladinu laktoferinu u psa a analyzovat jeho možnou roli na snížení aktivita lymfocytů u fen s pyometrou. Po sérii testů autoři dospěli k závěru, že i když feny s pyometrou mají zvýšenou hladinu laktoferinu, (cs)
- Lactoferrin is an 80 kDa glycoprotein belonging to the family of non-heme iron-binding monomeric glycoproteins. Lactoferrin affects both proliferation and differentiation of immune cells through its ability to modulate cellular signaling pathways.It was generally accepted that dogs produce very limited amount of lactoferrin (if any). In 2007, the lactoferrin was visualized in dog neutrophils using flow cytometry, simultaneously it was isolated from the neutrophils and its high resembling properties with human lactoferrin were demonstrated. Pyometra is a serious disease syndrome affecting mainly older nulliparous bitches in the luteal stage of the sexual cycle and is associated with neutrophilia and impaired some immune functions including activity of lymphocytes. A wide range of factors including lactoferrin has been proposed to explain this inhibition. The aim of this work was to measure lactoferrin concentration in the dog and analyze its possible role in a suppressed lymphocyte activity in bitches
- Lactoferrin is an 80 kDa glycoprotein belonging to the family of non-heme iron-binding monomeric glycoproteins. Lactoferrin affects both proliferation and differentiation of immune cells through its ability to modulate cellular signaling pathways.It was generally accepted that dogs produce very limited amount of lactoferrin (if any). In 2007, the lactoferrin was visualized in dog neutrophils using flow cytometry, simultaneously it was isolated from the neutrophils and its high resembling properties with human lactoferrin were demonstrated. Pyometra is a serious disease syndrome affecting mainly older nulliparous bitches in the luteal stage of the sexual cycle and is associated with neutrophilia and impaired some immune functions including activity of lymphocytes. A wide range of factors including lactoferrin has been proposed to explain this inhibition. The aim of this work was to measure lactoferrin concentration in the dog and analyze its possible role in a suppressed lymphocyte activity in bitches (en)
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| Title
| - Lactoferrin in the dog: a pyometra story
- Lactoferrin in the dog: a pyometra story (en)
- Laktoferin u feny : příběh pyometry (cs)
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| skos:prefLabel
| - Lactoferrin in the dog: a pyometra story
- Lactoferrin in the dog: a pyometra story (en)
- Laktoferin u feny : příběh pyometry (cs)
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| skos:notation
| - RIV/62157124:16170/08:00001970!RIV09-MZE-16170___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/62157124:16170/08:00001970
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Lactoferrin; bitch; pyometra (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...v/mistoKonaniAkce
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...ocetUcastnikuAkce
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| http://linked.open...nichUcastnikuAkce
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/statKonaniAkce
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| http://linked.open...iv/tvurceVysledku
| - Faldyna, Martin
- Bartošková, Alena
- Vitásek, Roman
- Adlerová, L.
- Levá, L.
- Kudláčková, H.
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| http://linked.open...vavai/riv/typAkce
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| http://linked.open.../riv/ukonceniAkce
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| http://linked.open.../riv/zahajeniAkce
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| http://linked.open...n/vavai/riv/zamer
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| http://localhost/t...ganizacniJednotka
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