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  • Předmětem bylo zjištění, zda apoptóza neutrofilů a jejich eliminace makrofágy jsou modulovány infekcí Streptococcus uberis. 24 h po intramammární aplikaci PBS a S. uberis došlo ke zvýšení počtu Annexin V+/PI- a karyopyknotických neutrofilů. Nejvyšší procentuální zastoupení těchto buněk bylo detekováno 72h po PBS a S. uberis. Nejvyšší procento karyopyknotických neutrofilů bylo detekováno 72h po PBS a 168 h po S. uberis. Celkový počet myeloperoxidáza pozitivních makrofágů byl nejvyšší 24 h po PBS a 72 h po S. uberis. Procentické zastoupení těchto buněk bylo nejvyšší 72 h po PBS a zároveň u S. uberis. Výsledky této studie demonstrují, že experimentální infekce mléčné žlázy skotu S. uberis moduluje apoptózu neutrofilních granulocytů. (cs)
  • The object of the study was to determine if apoptosis of neutrophils and their subsequent elimination from the mammary gland by macrophages are modulated by an infection of Streptococcus uberis. After PBS and S. uberis administration the total number of both Annexin V+/PI- neutrophils and karyopycnotic neutrophils peaked at 24 hours. The highest percentages of Annexin V+/PI- neutrophils were detected at 72 hours after PBS and S. uberis, respectively. The highest percentages of karyopycnotic neutrophils were detected at 72 hours after PBS and 168 hours after S. uberis, respectively. The total number of MPO+ macrophages was the highest at 24 hour after PBS and 72 hours after S. uberis. The percentage of MPO+ macrophages was the highest at 72 hours after PBS and S. uberis. The results of this study demonstrate that during experimental infection of the mammary gland by S. uberis, the apoptosis of neutrophils is modulated.
  • The object of the study was to determine if apoptosis of neutrophils and their subsequent elimination from the mammary gland by macrophages are modulated by an infection of Streptococcus uberis. After PBS and S. uberis administration the total number of both Annexin V+/PI- neutrophils and karyopycnotic neutrophils peaked at 24 hours. The highest percentages of Annexin V+/PI- neutrophils were detected at 72 hours after PBS and S. uberis, respectively. The highest percentages of karyopycnotic neutrophils were detected at 72 hours after PBS and 168 hours after S. uberis, respectively. The total number of MPO+ macrophages was the highest at 24 hour after PBS and 72 hours after S. uberis. The percentage of MPO+ macrophages was the highest at 72 hours after PBS and S. uberis. The results of this study demonstrate that during experimental infection of the mammary gland by S. uberis, the apoptosis of neutrophils is modulated. (en)
Title
  • The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis
  • The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis (en)
  • Role apoptózy neutrofilních granulocytů během experimentální infekce mléčné žlázy Streptococcus uberis (cs)
skos:prefLabel
  • The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis
  • The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis (en)
  • Role apoptózy neutrofilních granulocytů během experimentální infekce mléčné žlázy Streptococcus uberis (cs)
skos:notation
  • RIV/62156489:43210/06:00095107!RIV07-GA0-43210___
http://linked.open.../vavai/riv/strany
  • 265;277
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA524/03/1531)
http://linked.open...iv/cisloPeriodika
  • 51
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 497890
http://linked.open...ai/riv/idVysledku
  • RIV/62156489:43210/06:00095107
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • apoptosis; neutrophils; streptococcus uberis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [B67EE01A71DB]
http://linked.open...i/riv/nazevZdroje
  • Veterinary Medicine Czech
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Faldyna, Martin
  • Ryšánek, Dušan
  • Sládek, Zbyšek
  • Rýznarová, Helena
issn
  • 0375-8427
number of pages
http://localhost/t...ganizacniJednotka
  • 43210
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