About: Solid-Phase Synthesis of Trisubstituted 2,5-Dihydrobenzo[f]thiadiazepine 1,1-Dioxide Derivatives     Goto   Sponge   NotDistinct   Permalink

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Description
  • The solid-phase synthesis of trisubstituted 2,5-dihydrobenzo[f]thiadiazepine 1,1-dioxides is reported. Acyclic polymer-supported intermediates were prepared using commercially available building blocks: Fmoc-protected amino acids, 2-nitrobenzenesulfonyl chlorides, and bromoketones. The acyclic precursors underwent acid-mediated release from the resin and the cyclization was completed in solution.
  • The solid-phase synthesis of trisubstituted 2,5-dihydrobenzo[f]thiadiazepine 1,1-dioxides is reported. Acyclic polymer-supported intermediates were prepared using commercially available building blocks: Fmoc-protected amino acids, 2-nitrobenzenesulfonyl chlorides, and bromoketones. The acyclic precursors underwent acid-mediated release from the resin and the cyclization was completed in solution. (en)
Title
  • Solid-Phase Synthesis of Trisubstituted 2,5-Dihydrobenzo[f]thiadiazepine 1,1-Dioxide Derivatives
  • Solid-Phase Synthesis of Trisubstituted 2,5-Dihydrobenzo[f]thiadiazepine 1,1-Dioxide Derivatives (en)
skos:prefLabel
  • Solid-Phase Synthesis of Trisubstituted 2,5-Dihydrobenzo[f]thiadiazepine 1,1-Dioxide Derivatives
  • Solid-Phase Synthesis of Trisubstituted 2,5-Dihydrobenzo[f]thiadiazepine 1,1-Dioxide Derivatives (en)
skos:notation
  • RIV/61989592:15310/14:33151963!RIV15-MSM-15310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(EE2.4.31.0130), P(GAP207/12/0473)
http://linked.open...iv/cisloPeriodika
  • 8
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 45895
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15310/14:33151963
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • amino acids, benzothiadiazepines, bromoketones, cyclative cleavage, nitrobenzenesulfonyl chlorides, solid-phase synthesis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [466B438E232B]
http://linked.open...i/riv/nazevZdroje
  • ACS Combinatorial Science
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 16
http://linked.open...iv/tvurceVysledku
  • Krchňák, Viktor
  • Fülöpová, Veronika
http://linked.open...ain/vavai/riv/wos
  • 000340344500007
issn
  • 2156-8952
number of pages
http://bibframe.org/vocab/doi
  • 10.1021/co500084k
http://localhost/t...ganizacniJednotka
  • 15310
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