About: Methods of speciation analysis of arsenic in food and nutritional supplements by liquid chromatography inductively coupled plasma mass spectrometry (ICP-MS)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Speciation analysis plays an important role in analysis of food and food supplements. Food is the most obvious mean of transport for toxic elements to enter the human body. The identification and determination of the element species is necessary for an accurate risk assessment. While the toxic inorganic arsenic (AsIII and AsV) have been proven as carcinogenic compounds, methylated forms of arsenic such as methylarsenic acid (MMA) and dimethylarsenic acid (DMA) are significantly less toxic. Finally, other well-known species such arsenobetaine (AsB), arsenocholine (AsC) and arsenosugars (AsSs) are considered to be non-toxic. This review focuses on basic principles of HPLC and advantages and limitations of using ICP-MS as a detector for arsenic speciation. Important aspects of analytical procedures used in analysis of food and food supplements including column, extraction method, mobile phases and separation conditions and validation parameters are also presented. Speciation analysis plays an important role in analysis of food and food supplements. Food is the most obvious mean of transport for toxic elements to enter the human body. The identification and determination of the element species is necessary for an accurate risk assessment. While the toxic inorganic arsenic (AsIII and AsV) have been proven as carcinogenic compounds, methylated forms of arsenic such as methylarsenic acid (MMA) and dimethylarsenic acid (DMA) are significantly less toxic. Finally, other well-known species such arsenobetaine (AsB), arsenocholine (AsC) and arsenosugars (AsSs) are considered to be non-toxic. This review focuses on basic principles of HPLC and advantages and limitations of using ICP-MS as a detector for arsenic speciation. Important aspects of analytical procedures used in analysis of food and food supplements including column, extraction method, mobile phases and separation conditions and validation parameters are also presented. (en)
Title	Methods of speciation analysis of arsenic in food and nutritional supplements by liquid chromatography inductively coupled plasma mass spectrometry (ICP-MS) Methods of speciation analysis of arsenic in food and nutritional supplements by liquid chromatography inductively coupled plasma mass spectrometry (ICP-MS) (en)
skos:prefLabel	Methods of speciation analysis of arsenic in food and nutritional supplements by liquid chromatography inductively coupled plasma mass spectrometry (ICP-MS) Methods of speciation analysis of arsenic in food and nutritional supplements by liquid chromatography inductively coupled plasma mass spectrometry (ICP-MS) (en)
skos:notation	RIV/61989592:15310/12:33143252!RIV13-MSM-15310___
http://linked.open...avai/predkladatel	Přírodovědecká fakulta
http://linked.open...avai/riv/aktivita	S
http://linked.open...avai/riv/aktivity	S
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Štěpánková, Kamila Milde, David
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	149790
http://linked.open...ai/riv/idVysledku	RIV/61989592:15310/12:33143252
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	arsenic speciation, HPLC-ICP-MS, food (en)
http://linked.open.../riv/klicoveSlovo	arsenic speciation HPLC-ICP-MS food
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[85C5FE32F7B3]
http://linked.open...i/riv/nazevZdroje	Acta Universitatis Palackianae Olomucensis, Facultas Rerum Naturalium, Chemica
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	52
http://linked.open...iv/tvurceVysledku	Štěpánková, Kamila Milde, David Šimáková, Alena
issn	0232-0061
number of pages	22 (xsd:int)
http://localhost/t...ganizacniJednotka	15310
is http://linked.open...avai/riv/vysledek of	Methods of speciation analysis of arsenic in food and nutritional supplements by liquid chromatography inductively coupled plasma mass spectrometry (ICP-MS)

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