About: Innovations in Biomolecular Modeling and Simulations (Vol. 2 Chap. 6): Molecular Dynamics Simulations of RNA Molecules

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Description	The central role of RNA in numerous biological processes including translation, protein localization, gene regulation, RNA processing, and viral replication calls for a detailed understanding of RNA function, structure, and conformational dynamics. Accompanying and enhancing our increasing appreciation of RNA is the rapidly expanding availability of high-resolution structures of RNAs and RNA-protein (RNP) complexes. These atomic resolution snapshots provide detailed rationalization for existing biochemical data. However, biological function depends on the dynamic evolution of structures along functional pathways. A complete understanding of the relevant structural dynamics exhibited by RNA requires monitoring timescales from picoseconds to hours through the application of a correspondingly broad range of techniques, with careful consideration given to the scope and limitation of each approach. The central role of RNA in numerous biological processes including translation, protein localization, gene regulation, RNA processing, and viral replication calls for a detailed understanding of RNA function, structure, and conformational dynamics. Accompanying and enhancing our increasing appreciation of RNA is the rapidly expanding availability of high-resolution structures of RNAs and RNA-protein (RNP) complexes. These atomic resolution snapshots provide detailed rationalization for existing biochemical data. However, biological function depends on the dynamic evolution of structures along functional pathways. A complete understanding of the relevant structural dynamics exhibited by RNA requires monitoring timescales from picoseconds to hours through the application of a correspondingly broad range of techniques, with careful consideration given to the scope and limitation of each approach. (en)
Title	Innovations in Biomolecular Modeling and Simulations (Vol. 2 Chap. 6): Molecular Dynamics Simulations of RNA Molecules Innovations in Biomolecular Modeling and Simulations (Vol. 2 Chap. 6): Molecular Dynamics Simulations of RNA Molecules (en)
skos:prefLabel	Innovations in Biomolecular Modeling and Simulations (Vol. 2 Chap. 6): Molecular Dynamics Simulations of RNA Molecules Innovations in Biomolecular Modeling and Simulations (Vol. 2 Chap. 6): Molecular Dynamics Simulations of RNA Molecules (en)
skos:notation	RIV/61989592:15310/12:33142852!RIV13-MSM-15310___
http://linked.open...avai/predkladatel	Přírodovědecká fakulta
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED2.1.00/03.0058), P(GPP301/11/P558), P(IAA400040802)
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Otyepka, Michal Banáš, Pavel
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	141927
http://linked.open...ai/riv/idVysledku	RIV/61989592:15310/12:33142852
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Molecular dynamics, RNA, RNP (en)
http://linked.open.../riv/klicoveSlovo	Molecular dynamics RNA RNP
http://linked.open...ontrolniKodProRIV	[ADD6DF87FEE5]
http://linked.open...i/riv/mistoVydani	Cambridge UK
http://linked.open...vEdiceCisloSvazku	RSC biomolecular sciences, no. 23-24
http://linked.open...i/riv/nazevZdroje	Innovations in Biomolecular Modeling and Simulations Volume 2
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...v/pocetStranKnihy	350 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Regional Centre of Advanced Technologies and Materials Structure, dynamics, and reaction mechanism of catalytic RNA Mechanism of catalytical self-cleavage of two non-coding RNAs of human patogens
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Otyepka, Michal Réblová, Kamila Šponer, Jiří Banáš, Pavel Walter, Nils
number of pages	27 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Royal Society of Chemistry
https://schema.org/isbn	978-1-84973-462-2
http://localhost/t...ganizacniJednotka	15310
is http://linked.open...avai/riv/vysledek of	Innovations in Biomolecular Modeling and Simulations (Vol. 2 Chap. 6): Molecular Dynamics Simulations of RNA Molecules

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