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Description
| - 2-Phenyl-3-hydroxy-4(1H)-quinolinones can be considered as aza-analogues of flavones, compounds which are known for the wide-range of their biological activity. These quinolinones were studied as inhibitors of topoisomerase, gyrase and IMPDH. They were tested for anticancer activity in-vitro and were also shown to possess immunosuppressive properties. This review is the first summarizing the synthesis and activity of the mentioned quinolinones.
- 2-Phenyl-3-hydroxy-4(1H)-quinolinones can be considered as aza-analogues of flavones, compounds which are known for the wide-range of their biological activity. These quinolinones were studied as inhibitors of topoisomerase, gyrase and IMPDH. They were tested for anticancer activity in-vitro and were also shown to possess immunosuppressive properties. This review is the first summarizing the synthesis and activity of the mentioned quinolinones. (en)
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Title
| - 3-Hydroxy-2-phenyl-4(1H)-quinolinones as promising biologically active compounds
- 3-Hydroxy-2-phenyl-4(1H)-quinolinones as promising biologically active compounds (en)
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skos:prefLabel
| - 3-Hydroxy-2-phenyl-4(1H)-quinolinones as promising biologically active compounds
- 3-Hydroxy-2-phenyl-4(1H)-quinolinones as promising biologically active compounds (en)
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skos:notation
| - RIV/61989592:15310/09:10214125!RIV11-MSM-15310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(LC07017), S, Z(MSM6198959216), Z(MSM6198959223)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15310/09:10214125
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - 2-Phenyl-3-hydroxy-4(1H)-quinolinones (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Mini Reviews in Medicinal Chemistry
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Hajdúch, Marián
- Hlaváč, Jan
- Kolář, Milan
- Soural, Miroslav
- Hradil, Pavel
- Večeřová, Renata
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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is http://linked.open...avai/riv/vysledek
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