About: Aminoaldehydes: reactive products of polyamine degradation

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The oxidative degradation of diamines and polyamines catalyzed by amine oxidases produces ω-aminoaldehydes and hydrogen peroxide. ω-Aminoaldehydes may also be produced from their precursors nonoxidatively by a pyridoxal-phosphate dependent aminotransferase reaction. 3-Aminopropionaldehyde and 4-aminobutyraldehyde belong to the best substrates of NAD(P)+-dependent aminoaldehyde dehydrogenase. In this way they are oxidized to β-alanine and 4-aminobutyric acid. 4-Aminobutyraldehyde and 5-aminovaleraldehyde spontaneously cyclize to 1-pyrroline and 1-piperideine, respectively. The heterocycles are subsequently utilized in the production of several types of alkaloids. 4-Aminobutyraldehyde has recently been identified as the precursor of another kind of secondary metabolite, 2-acetyl-1-pyrroline, causing fragrance in certain rice varieties. 3-Aminopropionaldehyde is known as a potent cytotoxin. It is associated with certain diseases like cerebral ischemia and stroke. The oxidative degradation of diamines and polyamines catalyzed by amine oxidases produces ω-aminoaldehydes and hydrogen peroxide. ω-Aminoaldehydes may also be produced from their precursors nonoxidatively by a pyridoxal-phosphate dependent aminotransferase reaction. 3-Aminopropionaldehyde and 4-aminobutyraldehyde belong to the best substrates of NAD(P)+-dependent aminoaldehyde dehydrogenase. In this way they are oxidized to β-alanine and 4-aminobutyric acid. 4-Aminobutyraldehyde and 5-aminovaleraldehyde spontaneously cyclize to 1-pyrroline and 1-piperideine, respectively. The heterocycles are subsequently utilized in the production of several types of alkaloids. 4-Aminobutyraldehyde has recently been identified as the precursor of another kind of secondary metabolite, 2-acetyl-1-pyrroline, causing fragrance in certain rice varieties. 3-Aminopropionaldehyde is known as a potent cytotoxin. It is associated with certain diseases like cerebral ischemia and stroke. (en)
Title	Aminoaldehydes: reactive products of polyamine degradation Aminoaldehydes: reactive products of polyamine degradation (en)
skos:prefLabel	Aminoaldehydes: reactive products of polyamine degradation Aminoaldehydes: reactive products of polyamine degradation (en)
skos:notation	RIV/61989592:15310/09:00010913!RIV10-GA0-15310___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA522/08/0555)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Šebela, Marek Duchoslav, Martin
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	302640
http://linked.open...ai/riv/idVysledku	RIV/61989592:15310/09:00010913
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	aminoaldehyde; aminoaldehyde dehydrogenase; amine oxidase; polyamine degradation (en)
http://linked.open.../riv/klicoveSlovo	amine oxidase aminoaldehyde polyamine degradation aminoaldehyde dehydrogenase
http://linked.open...ontrolniKodProRIV	[ABCC57A196BB]
http://linked.open...i/riv/mistoVydani	Kerala, India
http://linked.open...i/riv/nazevZdroje	Biologically Active Amines and Related Enzymes? Biochemical, Physiological and Clinical Aspects (Toninello A., ed.)
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...v/pocetStranKnihy	300 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Structure-functional characterization of oxidoreductases acting on nitrogenous regulatory compounds in plants
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Duchoslav, Martin Šebela, Marek
number of pages	24 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Research Signpost, Transworld Research Network
https://schema.org/isbn	978-81-7895-433-2
http://localhost/t...ganizacniJednotka	15310
is http://linked.open...avai/riv/vysledek of	Aminoaldehydes: reactive products of polyamine degradation Aminoaldehydes: reactive products of polyamine degradation Aminoaldehydes: reactive products of polyamine degradation Aminoaldehydes: reactive products of polyamine degradation

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