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Description
  • The present invention relates to the use of a compound of formula (I), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, in the preparation of a medicament for treating a patient suffering from leukaemia, cancer or other proliferative disorder. A further embodiment relates to the use a compound of formula (I) in an assay for detecting the phosphorylation state of cellular substrates. The present invention also relates to novel compounds of formula (I), and the chemical synthesis thereof.
  • The present invention relates to the use of a compound of formula (I), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, in the preparation of a medicament for treating a patient suffering from leukaemia, cancer or other proliferative disorder. A further embodiment relates to the use a compound of formula (I) in an assay for detecting the phosphorylation state of cellular substrates. The present invention also relates to novel compounds of formula (I), and the chemical synthesis thereof. (en)
Title
  • Triterpenoid derivatives and their use as antiproliferative agents
  • Triterpenoid derivatives and their use as antiproliferative agents (en)
skos:prefLabel
  • Triterpenoid derivatives and their use as antiproliferative agents
  • Triterpenoid derivatives and their use as antiproliferative agents (en)
skos:notation
  • RIV/61989592:15310/05:10223264!RIV12-MSM-15310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM6198959216)
http://linked.open...cisloPatentuVzoru
  • EP1289977
http://linked.open...eleniPatentuVzoru
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 547334
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15310/05:10223264
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • modification; lupane; derivatives; cytotoxic; antitumour activity; betulinic acid; betulin (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [FA1C7D33341C]
http://linked.open.../licencniPoplatek
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  • Munich, The Hague, Berlin, Vienna, Brussels
http://linked.open...atelePatentuVzoru
  • Evropský patentový úřad
http://linked.open...in/vavai/riv/obor
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http://linked.open...iv/tvurceVysledku
  • Hajdúch, Marián
  • Šarek, Jan
http://linked.open...mniOchranaPatentu
http://linked.open...avai/riv/vlastnik
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http://linked.open...uzitiPatentuVzoru
http://linked.open...n/vavai/riv/zamer
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  • Univerzita Palackého v Olomouci; Univerzita Karlova v Praze;
http://localhost/t...ganizacniJednotka
  • 15310
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