About: Reactions of plant amine oxidases with N6-aminoalkyl derivatives of adenine

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	V práci je studována reakce rostlinných aminoxidas s N6-aminoalkylderiváty adeninu. (cs) Plant copper-containing amine oxidases (CAOs, EC 1.4.3.6) catalyze the oxidation of various amines. Once there was a hypothesis that the enzymes could oxidize cytokinins - plant hormones derived from adenine1, however, it has been shown that they rather cause inhibition2. Here we report a study on the reactions of three plant CAOs from grass pea (Lathyrus sativus), lentil (Lens esculenta) and a Mediterranean shrub (Euphorbia characias) with synthetic N6-aminoalkyl derivatives of adenine representing combined analogues of cytokinins and polyamines. The following compounds were prepared using an established method: N6-(3-aminopropyl)adenine, APAD; N6-(4-aminobutyl)adenine, ABAD; N6-(4-amino-trans-but-2-enyl)adenine, ATBAD; N6-(4-amino-cis-but-2-enyl)adenine, ACBAD and N6-(4-aminobut-2-ynyl)adenine, ABYAD. First, reaction rates of enzymatic oxidation were measured to decide between substrate and inhibitory properties. Two of the studied adenine derivatives were found to be substrates (ABAD, ATBAD) and th Plant copper-containing amine oxidases (CAOs, EC 1.4.3.6) catalyze the oxidation of various amines. Once there was a hypothesis that the enzymes could oxidize cytokinins - plant hormones derived from adenine1, however, it has been shown that they rather cause inhibition2. Here we report a study on the reactions of three plant CAOs from grass pea (Lathyrus sativus), lentil (Lens esculenta) and a Mediterranean shrub (Euphorbia characias) with synthetic N6-aminoalkyl derivatives of adenine representing combined analogues of cytokinins and polyamines. The following compounds were prepared using an established method: N6-(3-aminopropyl)adenine, APAD; N6-(4-aminobutyl)adenine, ABAD; N6-(4-amino-trans-but-2-enyl)adenine, ATBAD; N6-(4-amino-cis-but-2-enyl)adenine, ACBAD and N6-(4-aminobut-2-ynyl)adenine, ABYAD. First, reaction rates of enzymatic oxidation were measured to decide between substrate and inhibitory properties. Two of the studied adenine derivatives were found to be substrates (ABAD, ATBAD) and th (en)
Title	Reakce rostlinných aminoxidas s N6-aminoalkylderiváty adeninu (cs) Reactions of plant amine oxidases with N6-aminoalkyl derivatives of adenine Reactions of plant amine oxidases with N6-aminoalkyl derivatives of adenine (en)
skos:prefLabel	Reakce rostlinných aminoxidas s N6-aminoalkylderiváty adeninu (cs) Reactions of plant amine oxidases with N6-aminoalkyl derivatives of adenine Reactions of plant amine oxidases with N6-aminoalkyl derivatives of adenine (en)
skos:notation	RIV/61989592:15310/04:00002168!RIV/2005/MSM/153105/N
http://linked.open.../vavai/riv/strany	44-45
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM 153100010)
http://linked.open...iv/cisloPeriodika	S
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Peč, Pavel Šebela, Marek Maloň, Michal Fryčák, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	583622
http://linked.open...ai/riv/idVysledku	RIV/61989592:15310/04:00002168
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	amine oxidase;adenine;cytokinin;cytokinin oxidase/dehydrogenase;polyamine (en)
http://linked.open.../riv/klicoveSlovo	cytokinin amine oxidase cytokinin oxidase/dehydrogenase adenine polyamine
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[F75555DD7BD7]
http://linked.open...i/riv/nazevZdroje	Acta Universitatis Palackianae Olomucensis, Facultas Rerum Naturalium, Chemica
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	43
http://linked.open...iv/tvurceVysledku	Šebela, Marek Maloň, Michal Fryčák, Petr Floris, Giovanni Medda, Rosaria Peč, Pavel Lamplot, Zbyněk Longu, Silvia Padiglia, Alessandra
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20153100010
issn	0232-0061
number of pages	275 (xsd:int)
http://localhost/t...ganizacniJednotka	15310

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