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rdf:type
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Description
| - A method based on the coupling of capillary electrophoresis with mass spectrometry (CE/MS) was developed for the monitoring of 3-quinuclidinol and its four N-alkyl derivatives (methyl, ethyl, propyl and isopropyl derivatives). A fragmentation study (collision-induced dissociation of ions in an ion trap) and optimization of the ion optics set-up for CE/MS experiments using direct infusion of a methanolic solution of the standards into the mass spectrometer were carried out in advance. Molecular ions ofall quaternary compounds and the quasi-molecular ion [M + H](+) of free 3-quinuclidinol prevail in the mass spectra. In the MS/MS of propyl and isopropyl derivatives, the elimination of the alkyl chain dominates, leading to the ion at m/z 128. The fragm entation of the other compounds is more complex. Previous CE separation of the mixture of isobaric propyl and isopropyl derivatives is necessary for their unambiguous identification. A 10 mm ammonium acetate buffer (pH 4.0) is the optimum running electro
- A method based on the coupling of capillary electrophoresis with mass spectrometry (CE/MS) was developed for the monitoring of 3-quinuclidinol and its four N-alkyl derivatives (methyl, ethyl, propyl and isopropyl derivatives). A fragmentation study (collision-induced dissociation of ions in an ion trap) and optimization of the ion optics set-up for CE/MS experiments using direct infusion of a methanolic solution of the standards into the mass spectrometer were carried out in advance. Molecular ions ofall quaternary compounds and the quasi-molecular ion [M + H](+) of free 3-quinuclidinol prevail in the mass spectra. In the MS/MS of propyl and isopropyl derivatives, the elimination of the alkyl chain dominates, leading to the ion at m/z 128. The fragm entation of the other compounds is more complex. Previous CE separation of the mixture of isobaric propyl and isopropyl derivatives is necessary for their unambiguous identification. A 10 mm ammonium acetate buffer (pH 4.0) is the optimum running electro (en)
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Title
| - Capillary electrophoresis/mass spectrometry: a promising tool for the control of some physiologically hazardous compounds. I - Derivatives of 3-quinuclidinol
- Capillary electrophoresis/mass spectrometry: a promising tool for the control of some physiologically hazardous compounds. I - Derivatives of 3-quinuclidinol (en)
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skos:prefLabel
| - Capillary electrophoresis/mass spectrometry: a promising tool for the control of some physiologically hazardous compounds. I - Derivatives of 3-quinuclidinol
- Capillary electrophoresis/mass spectrometry: a promising tool for the control of some physiologically hazardous compounds. I - Derivatives of 3-quinuclidinol (en)
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skos:notation
| - RIV/61989592:15310/02:00001413!RIV/2003/MSM/153103/N
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15310/02:00001413
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - 3-quinuclidinol; quaternary ammonium salt; capillary electrophoresis; electrospray ionization; mass spectrometry; capillary electrophoresis/mass spectrometry (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Mass Spectrometry
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...ocetUcastnikuAkce
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http://linked.open...nichUcastnikuAkce
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Barták, Petr
- Bednář, Petr
- Hlaváč, Jan
- Lemr, Karel
- Ševčík, Juraj
- Stýskala, Jakub
- Stránský, Zdeněk
- Wiedermanová, Iveta
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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