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  • Insulin resistence associated with dyslipidemia enhances cardiovascular risk. Several atherogenic indexes have been suggested to give more precise information about the risk. The aim of our study was to estimate, which atherogenic index correlates better with parameters of insulin resistence. Furhemore, we compared the parameters of lipid metabolism and insulin resistence between smokers and non-smokers. In our cross-sectional study we enrolled 729 patients with dyslipidemia which were divided into two groups -non-smokers (586) and smokers (143) We measured lipid profile, parameters of insulin resistence and calculated atherogenic indexes - atherogenic index of plasma. AIP was found out to show stronger correlations with parameters of insulin resistence than other indexes (ApoB/ApoA1 or nonHDL cholesterol). AIP correlated with parameters of insulin resistence both in smokers and non-smokers, but after adjustment persisting only in non-smokers. Smokers had a wider waist circumference and a proatherogenic lipid profile. Smoking increases the risk of developing metabolic syndrome. AIP can be used in daily praxis for predicting insulin resistence in patients with dyslipidemia, predominantly in non-smokers.
  • Insulin resistence associated with dyslipidemia enhances cardiovascular risk. Several atherogenic indexes have been suggested to give more precise information about the risk. The aim of our study was to estimate, which atherogenic index correlates better with parameters of insulin resistence. Furhemore, we compared the parameters of lipid metabolism and insulin resistence between smokers and non-smokers. In our cross-sectional study we enrolled 729 patients with dyslipidemia which were divided into two groups -non-smokers (586) and smokers (143) We measured lipid profile, parameters of insulin resistence and calculated atherogenic indexes - atherogenic index of plasma. AIP was found out to show stronger correlations with parameters of insulin resistence than other indexes (ApoB/ApoA1 or nonHDL cholesterol). AIP correlated with parameters of insulin resistence both in smokers and non-smokers, but after adjustment persisting only in non-smokers. Smokers had a wider waist circumference and a proatherogenic lipid profile. Smoking increases the risk of developing metabolic syndrome. AIP can be used in daily praxis for predicting insulin resistence in patients with dyslipidemia, predominantly in non-smokers. (en)
Title
  • Correlation of lipid parameters and markers of insulin resistance: does smoking make a difference?
  • Correlation of lipid parameters and markers of insulin resistance: does smoking make a difference? (en)
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  • Correlation of lipid parameters and markers of insulin resistance: does smoking make a difference?
  • Correlation of lipid parameters and markers of insulin resistance: does smoking make a difference? (en)
skos:notation
  • RIV/61989592:15110/14:33151939!RIV15-MSM-15110___
http://linked.open...avai/riv/aktivita
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  • 9007
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  • RIV/61989592:15110/14:33151939
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  • atherogenic index; smoking habit; lipid metabolism; metabolic syndrome; insulin resistence (en)
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  • CZ - Česká republika
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  • [0DC4B241B2BB]
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  • Physiological Research (print)
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  • 63
http://linked.open...iv/tvurceVysledku
  • Langová, Kateřina
  • Vaverková, Helena
  • Karásek, David
  • Novotný, Dalibor
  • Lukeš, Jiří
  • Orság, Jiří
  • Cibičková, Lubica
issn
  • 0862-8408
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  • 15110
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