About: Self-renewal of Embryonic Stem Cells: Cell Cycle Regulation     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • Embryonic stem cells (ESCs) have an unusual cell cycle structure with a short G1 phase and with the largest proportion of cells in the S phase. During differentiation, the ESC cycle is readily remodeled and a prominent G1 phase is established. Recently, prolongation of G1 phase has been shown to be sufficient to induce ESC differentiation and, on the other hand, remodeling of cell cycle to an ESC-like cell cycle has been found to be a crucial and rate-limiting step in the process of reprogramming of differentiated cells to induced pluripotent stem cells. The specific structure of ESC cycle has been suggested to be a general requirement for pluripotency and self-renewal and existence of several links between cell cycle machinery and core pluripotency factors has been proposed.
  • Embryonic stem cells (ESCs) have an unusual cell cycle structure with a short G1 phase and with the largest proportion of cells in the S phase. During differentiation, the ESC cycle is readily remodeled and a prominent G1 phase is established. Recently, prolongation of G1 phase has been shown to be sufficient to induce ESC differentiation and, on the other hand, remodeling of cell cycle to an ESC-like cell cycle has been found to be a crucial and rate-limiting step in the process of reprogramming of differentiated cells to induced pluripotent stem cells. The specific structure of ESC cycle has been suggested to be a general requirement for pluripotency and self-renewal and existence of several links between cell cycle machinery and core pluripotency factors has been proposed. (en)
Title
  • Self-renewal of Embryonic Stem Cells: Cell Cycle Regulation
  • Self-renewal of Embryonic Stem Cells: Cell Cycle Regulation (en)
skos:prefLabel
  • Self-renewal of Embryonic Stem Cells: Cell Cycle Regulation
  • Self-renewal of Embryonic Stem Cells: Cell Cycle Regulation (en)
skos:notation
  • RIV/61989592:15110/12:33143017!RIV13-MSM-15110___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 167362
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/12:33143017
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • self-renewal; G1 phase; embryonic stem cells; cell cycle (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [06C696F04131]
http://linked.open...i/riv/mistoVydani
  • Dordrecht
http://linked.open...vEdiceCisloSvazku
  • Therapeutic Applications in Disease and Injury Series: Stem Cells and Cancer Stem Cells, Vol. 6
http://linked.open...i/riv/nazevZdroje
  • Stem Cells and Cancer Stem Cells
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Koledová, Zuzana
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/978-94-007-2993-3_2
http://purl.org/ne...btex#hasPublisher
  • Springer Netherlands
https://schema.org/isbn
  • 978-94-007-2992-6
http://localhost/t...ganizacniJednotka
  • 15110
is http://linked.open...avai/riv/vysledek of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 112 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software