About: Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I-III breast cancer (HannaH study): a phase 3, open-label, multicentre, randomised trial     Goto   Sponge   NotDistinct   Permalink

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  • Background A subcutaneous formulation of trastuzumab has been developed, offering potential improvements in patient convenience and resource use compared with the standard intravenous infusion of the drug. We compared the pharmacokinetic profile, efficacy, and safety of the subcutaneous and intravenous formulations in patients with HER2-positive early breast cancer.
  • Background A subcutaneous formulation of trastuzumab has been developed, offering potential improvements in patient convenience and resource use compared with the standard intravenous infusion of the drug. We compared the pharmacokinetic profile, efficacy, and safety of the subcutaneous and intravenous formulations in patients with HER2-positive early breast cancer. (en)
Title
  • Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I-III breast cancer (HannaH study): a phase 3, open-label, multicentre, randomised trial
  • Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I-III breast cancer (HannaH study): a phase 3, open-label, multicentre, randomised trial (en)
skos:prefLabel
  • Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I-III breast cancer (HannaH study): a phase 3, open-label, multicentre, randomised trial
  • Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I-III breast cancer (HannaH study): a phase 3, open-label, multicentre, randomised trial (en)
skos:notation
  • RIV/61989592:15110/12:33140637!RIV13-MSM-15110___
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  • 172292
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  • RIV/61989592:15110/12:33140637
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  • therapy; epirubicin; paclitaxel; popultion; Chemotherapy (en)
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  • US - Spojené státy americké
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  • [DE559618DAC2]
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  • Lancet oncology
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  • 13
http://linked.open...iv/tvurceVysledku
  • Melichar, Bohuslav
  • Hegg, Roberto
  • Heinzmann, Dominik
  • Ismael, Gustavo
  • Jackisch, Christian
  • Kim, Sung-Bae
  • Lichinitser, Mikhail
  • Lum, Bert
  • Muehlbauer, Susanne
  • Pienkowski, Tadeusz
  • Semiglazov, Vladimir
issn
  • 1470-2045
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/S1470-2045(12)70329-7
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  • 15110
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