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| Description
| - The study aimed at in vivo assessment of the impact of administered red blood cells (RBCs) concentrates on the plasma levels of K+, lactate, pH, Na+, Ca++ and glucose, depending on the volume and age of administered products. At the same time, biochemical changes occurring during the storage of these products were studied in vitro. A group of 80 RBC unit samples was analyzed, with the samples being equally distributed throughout the recommended storage time of 1-35 days. We found that the age of RBC concentrate results in increased potassium and lactate levels and decreased pH, sodium and glucose levels in the RBC samples. The concentrations were in the following ranges: potassium 4.0-40.5 mmol/L; lactate 4.1-28.0 mmol/L; pH 7.0-6.65; sodium 137-116 mmol/L; glucose 29.0-14.0 mmol/L. At the same time, a prospectively selected group of 46 patients were administered a total of 354 RBC units. The mean age of RBC concentrates was 16.18 days. The number of administered RBC units ranged from 2 to 38, a mean of 7.7 RBC units/patient. The administration of 1 RBC unit was associated with a mean in vivo increase of the potassium level by 0.07 mmol/L and lactate level by 0.13 mmol/L. Only minimal changes were observed in pH, Na+, Ca++ and glucose levels. The administration of larger amounts of RBC concentrates may lead to an increase in the patient's plasma levels of potassium and lactate. This increase is proportional to the age and volume of RBCs.
- The study aimed at in vivo assessment of the impact of administered red blood cells (RBCs) concentrates on the plasma levels of K+, lactate, pH, Na+, Ca++ and glucose, depending on the volume and age of administered products. At the same time, biochemical changes occurring during the storage of these products were studied in vitro. A group of 80 RBC unit samples was analyzed, with the samples being equally distributed throughout the recommended storage time of 1-35 days. We found that the age of RBC concentrate results in increased potassium and lactate levels and decreased pH, sodium and glucose levels in the RBC samples. The concentrations were in the following ranges: potassium 4.0-40.5 mmol/L; lactate 4.1-28.0 mmol/L; pH 7.0-6.65; sodium 137-116 mmol/L; glucose 29.0-14.0 mmol/L. At the same time, a prospectively selected group of 46 patients were administered a total of 354 RBC units. The mean age of RBC concentrates was 16.18 days. The number of administered RBC units ranged from 2 to 38, a mean of 7.7 RBC units/patient. The administration of 1 RBC unit was associated with a mean in vivo increase of the potassium level by 0.07 mmol/L and lactate level by 0.13 mmol/L. Only minimal changes were observed in pH, Na+, Ca++ and glucose levels. The administration of larger amounts of RBC concentrates may lead to an increase in the patient's plasma levels of potassium and lactate. This increase is proportional to the age and volume of RBCs. (en)
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| Title
| - Biochemical changes in the patient's plasma after red blood cell transfusion
- Biochemical changes in the patient's plasma after red blood cell transfusion (en)
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| skos:prefLabel
| - Biochemical changes in the patient's plasma after red blood cell transfusion
- Biochemical changes in the patient's plasma after red blood cell transfusion (en)
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| skos:notation
| - RIV/61989592:15110/11:33116094!RIV12-MSM-15110___
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| http://linked.open...avai/predkladatel
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/11:33116094
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - lactate; hyperkalemia; transfusion; red blood cells (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - HR - Chorvatská republika
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Adamus, Milan
- Klementa, Bronislav
- Neiser, Jan
- Uvízl, Radovan
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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| is http://linked.open...avai/riv/vysledek
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