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rdf:type
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Description
| - IgA nephropathy (IgAN), the most common glomerulonephritis, is characterized by mesangial IgA1-containing immunodeposits, proliferation of mesangial cells, and matrix expansion. Clinical onset is frequently heralded by synpharyngitic hematuria, macroscopic hematuria during an upper-respiratory tract infection. Clinical and laboratory data support a postulated extrarenal origin of the glomerular IgA1, likely derived from circulating immune complexes containing polymeric IgA1, deficient in galactose in the hinge-region O-glycans, bound by antiglycan antibodies. This aberrant IgA1 is produced by IgA1-secreting cells with abnormal activities of specific glycosyltransferases.
- IgA nephropathy (IgAN), the most common glomerulonephritis, is characterized by mesangial IgA1-containing immunodeposits, proliferation of mesangial cells, and matrix expansion. Clinical onset is frequently heralded by synpharyngitic hematuria, macroscopic hematuria during an upper-respiratory tract infection. Clinical and laboratory data support a postulated extrarenal origin of the glomerular IgA1, likely derived from circulating immune complexes containing polymeric IgA1, deficient in galactose in the hinge-region O-glycans, bound by antiglycan antibodies. This aberrant IgA1 is produced by IgA1-secreting cells with abnormal activities of specific glycosyltransferases. (en)
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Title
| - Aberrant Glycosylation of IgA 1 and AntiGlycan Antibodies in IgA Nephropathy: Role of Mucosal Immune System
- Aberrant Glycosylation of IgA 1 and AntiGlycan Antibodies in IgA Nephropathy: Role of Mucosal Immune System (en)
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skos:prefLabel
| - Aberrant Glycosylation of IgA 1 and AntiGlycan Antibodies in IgA Nephropathy: Role of Mucosal Immune System
- Aberrant Glycosylation of IgA 1 and AntiGlycan Antibodies in IgA Nephropathy: Role of Mucosal Immune System (en)
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skos:notation
| - RIV/61989592:15110/11:10224921!RIV12-MZ0-15110___
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http://linked.open...avai/predkladatel
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GAP304/10/1951), P(NT11081)
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/11:10224921
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...v/mistoKonaniAkce
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http://linked.open...i/riv/mistoVydani
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http://linked.open...i/riv/nazevZdroje
| - Advances in Oto-Rhino-Laryngology
|
http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
| |
http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
| |
http://linked.open...iv/tvurceVysledku
| - Gharavi, Alli
- Julian, Bruce
- Moldoveanu, Zina
- Městacký, Jiří
- Novák, Jan
- RAŠKA, Milan
- Suzuki, Hitoshi
- Suzuki, Yusuke
- Tomino, Yusuhiko
- Wyatt, Robert
|
http://linked.open...vavai/riv/typAkce
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http://linked.open.../riv/zahajeniAkce
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issn
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number of pages
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http://purl.org/ne...btex#hasPublisher
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https://schema.org/isbn
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http://localhost/t...ganizacniJednotka
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is http://linked.open...avai/riv/vysledek
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