About: Dysfunction of hypothalamic-hypophysial axis after traumatic brain injury in adults: Clinical article     Goto   Sponge   NotDistinct   Permalink

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  • Object. Traumatic brain injury (TBI) is a major cause of serious morbidity and mortality. The incidence is 100-500/100,000 inhabitants/year. Chronic pituitary dysfunction is increasingly recognized after TBI. To define the incidence of endocrine dysfunction and risk factors, the authors describe a prospectively assessed group of patients in whom they documented hormonal functions, early diagnosis, and treatment of neuroendocrine dysfunction after TBI. Methods. Patients aged 18-65 years were prospectively observed from the time of injury to 1 year postinjury; the Glasgow Coma Scale score ranged from 3 to 14. Patients underwent evaluation of hormonal function at the time of injury and at 3, 6, and 12 months postinjury. Magnetic resonance imaging was also conducted at 1 year postinjury. Results. During the study period, 89 patients were observed. The mean age of the patients was 36 years, there were 23 women, and the median Glasgow Coma Scale score was 7.
  • Object. Traumatic brain injury (TBI) is a major cause of serious morbidity and mortality. The incidence is 100-500/100,000 inhabitants/year. Chronic pituitary dysfunction is increasingly recognized after TBI. To define the incidence of endocrine dysfunction and risk factors, the authors describe a prospectively assessed group of patients in whom they documented hormonal functions, early diagnosis, and treatment of neuroendocrine dysfunction after TBI. Methods. Patients aged 18-65 years were prospectively observed from the time of injury to 1 year postinjury; the Glasgow Coma Scale score ranged from 3 to 14. Patients underwent evaluation of hormonal function at the time of injury and at 3, 6, and 12 months postinjury. Magnetic resonance imaging was also conducted at 1 year postinjury. Results. During the study period, 89 patients were observed. The mean age of the patients was 36 years, there were 23 women, and the median Glasgow Coma Scale score was 7. (en)
Title
  • Dysfunction of hypothalamic-hypophysial axis after traumatic brain injury in adults: Clinical article
  • Dysfunction of hypothalamic-hypophysial axis after traumatic brain injury in adults: Clinical article (en)
skos:prefLabel
  • Dysfunction of hypothalamic-hypophysial axis after traumatic brain injury in adults: Clinical article
  • Dysfunction of hypothalamic-hypophysial axis after traumatic brain injury in adults: Clinical article (en)
skos:notation
  • RIV/61989592:15110/10:33115974!RIV12-MSM-15110___
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  • 255608
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  • RIV/61989592:15110/10:33115974
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  • Traumatic brain injury; Hypothalamic-hypophysial axis; Hypopituitarism (en)
http://linked.open.../riv/klicoveSlovo
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  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [4004DADC99A6]
http://linked.open...i/riv/nazevZdroje
  • Journal of Neurosurgery
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  • 113
http://linked.open...iv/tvurceVysledku
  • Zapletalová, Jiřina
  • Krahulík, David
  • Fryšák, Zdeněk
  • Vaverka, Miroslav
issn
  • 0022-3085
number of pages
http://localhost/t...ganizacniJednotka
  • 15110
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