About: CSF markers of neurodegeneration in Parkinson's disease     Goto   Sponge   NotDistinct   Permalink

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Description
  • Objective: Parkinson's disease (PD) is a chronic, progressive, neurodegenerative disease with a multifactorial etiology. Protein accumulation is speculated by some to play a prominent role in the pathogenesis of PD. The severity of neurodegeneration should correlate with cerebrospinal fluid (CSF) levels of these neurodegenerative markers (NDMs). The aims of the study were to assess the CSF levels of tau protein, beta-amyloid(1-42), cystatin C and clusterin in patients suffering from PD and in a control group, to compare the CSF levels between the two groups and to correlate them to PD duration.
  • Objective: Parkinson's disease (PD) is a chronic, progressive, neurodegenerative disease with a multifactorial etiology. Protein accumulation is speculated by some to play a prominent role in the pathogenesis of PD. The severity of neurodegeneration should correlate with cerebrospinal fluid (CSF) levels of these neurodegenerative markers (NDMs). The aims of the study were to assess the CSF levels of tau protein, beta-amyloid(1-42), cystatin C and clusterin in patients suffering from PD and in a control group, to compare the CSF levels between the two groups and to correlate them to PD duration. (en)
Title
  • CSF markers of neurodegeneration in Parkinson's disease
  • CSF markers of neurodegeneration in Parkinson's disease (en)
skos:prefLabel
  • CSF markers of neurodegeneration in Parkinson's disease
  • CSF markers of neurodegeneration in Parkinson's disease (en)
skos:notation
  • RIV/61989592:15110/10:10223403!RIV14-MZ0-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(NF7480), S, V
http://linked.open...iv/cisloPeriodika
  • 117
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 252464
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/10:10223403
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • neurodegeneration; CSF; clusterin; tau protein; Parkinson's disease (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • AT - Rakouská republika
http://linked.open...ontrolniKodProRIV
  • [0B8DA700B4A2]
http://linked.open...i/riv/nazevZdroje
  • Journal of Neural Transmission
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 10
http://linked.open...iv/tvurceVysledku
  • Mareš, Jan
  • Stejskal, David
  • Zapletalová, Jana
  • Kaňovský, Petr
  • Hluštík, Petr
  • Přikrylová Vranová, Hana
  • Nevrlý, Martin
http://linked.open...ain/vavai/riv/wos
  • 000284782100008
issn
  • 0300-9564
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s00702-010-0462-z
http://localhost/t...ganizacniJednotka
  • 15110
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