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  • An implant elicits a biological response in the surrounding tissue which determines the acceptance and long-term function of the implant. In our study we focused on the interaction between six different chemically and physically modified titanium implants (Tis-MALP, Tis-O, Tis-OA, Tis-OPAAE, Tis-OZ, Tis-OPAE) with alveolar fibroblasts as well as with five type of microorganisms (S. epidermis, S.mutans, S. gordonii, S. intermedius, C.albicans). The analysis of microorganism adhesion was determined by CFU (colony forming unite) and biofilm formation. The presence of ?3?1 and vinculin expression on alveolar fibroblasts was demonstrated using phospho specific cell based ELISA (PACE). Alveolar fibroblasts have the highest expression of these proteins on Tis-OPAAE and Tis-OPAE. It corresponds with results from bacterial adhesion and biofilm formation and it was related to the lowest production of collagen I by alveolar fibroblasts on Tis-OPAAE titanium disc.
  • An implant elicits a biological response in the surrounding tissue which determines the acceptance and long-term function of the implant. In our study we focused on the interaction between six different chemically and physically modified titanium implants (Tis-MALP, Tis-O, Tis-OA, Tis-OPAAE, Tis-OZ, Tis-OPAE) with alveolar fibroblasts as well as with five type of microorganisms (S. epidermis, S.mutans, S. gordonii, S. intermedius, C.albicans). The analysis of microorganism adhesion was determined by CFU (colony forming unite) and biofilm formation. The presence of ?3?1 and vinculin expression on alveolar fibroblasts was demonstrated using phospho specific cell based ELISA (PACE). Alveolar fibroblasts have the highest expression of these proteins on Tis-OPAAE and Tis-OPAE. It corresponds with results from bacterial adhesion and biofilm formation and it was related to the lowest production of collagen I by alveolar fibroblasts on Tis-OPAAE titanium disc. (en)
Title
  • Adherence of Alveolar Fibroblasts and Microorganisms on Titanium Implants
  • Adherence of Alveolar Fibroblasts and Microorganisms on Titanium Implants (en)
skos:prefLabel
  • Adherence of Alveolar Fibroblasts and Microorganisms on Titanium Implants
  • Adherence of Alveolar Fibroblasts and Microorganisms on Titanium Implants (en)
skos:notation
  • RIV/61989592:15110/10:10213171!RIV11-MSM-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(FI-IM5/218), Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 245441
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/10:10213171
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • adhesion; microorganisms; alveolar fibroblasts; titanium disc (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • TR - Turecká republika
http://linked.open...ontrolniKodProRIV
  • [3F0CF7973587]
http://linked.open...i/riv/nazevZdroje
  • World Academy of Science, Engineering and Technology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 64
http://linked.open...iv/tvurceVysledku
  • Ulrichová, Jitka
  • Růžička, Filip
  • Franková, Jana
  • Pivodová, Veronika
http://linked.open...n/vavai/riv/zamer
issn
  • 2070-3724
number of pages
http://localhost/t...ganizacniJednotka
  • 15110
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