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Description
| - Background: Nodal peripheral T-cell lymphomas (PTCLs) are infrequent subtypes of non-Hodgkin?s lymphomas.-The WHO classification recognizes three subgroups of nodal PTCL: peripheral T-cell lymphoma not otherwise specified-(PTCL, NOS), anaplastic large cell lymphoma (ALCL) and angioimmunoblastic lymphoma (AIL). The clinical-course is aggressive and despite multiagent chemotherapy, the median survival is about 2 years. Optimal first-line chemotherapy-is not established and the role of high-dose therapy with autologous stem cell support is still controversial.-Aim: To analyze the long-term outcome of PTCL patients treated with intensive first-line chemotherapy with highdose-therapy and autologous transplant consolidation. Method: Sequential chemotherapy protocol consisting of 3 cycles of CHOEP-21-like regimen (PACEBO), 1 cycle-of an ifosfamide and methotrexate-based regimen (IVAM) and a priming regimen with high-dose cytosine arabinoside-(HAM). Consolidation was provided with myeloablative conditioning (
- Background: Nodal peripheral T-cell lymphomas (PTCLs) are infrequent subtypes of non-Hodgkin?s lymphomas.-The WHO classification recognizes three subgroups of nodal PTCL: peripheral T-cell lymphoma not otherwise specified-(PTCL, NOS), anaplastic large cell lymphoma (ALCL) and angioimmunoblastic lymphoma (AIL). The clinical-course is aggressive and despite multiagent chemotherapy, the median survival is about 2 years. Optimal first-line chemotherapy-is not established and the role of high-dose therapy with autologous stem cell support is still controversial.-Aim: To analyze the long-term outcome of PTCL patients treated with intensive first-line chemotherapy with highdose-therapy and autologous transplant consolidation. Method: Sequential chemotherapy protocol consisting of 3 cycles of CHOEP-21-like regimen (PACEBO), 1 cycle-of an ifosfamide and methotrexate-based regimen (IVAM) and a priming regimen with high-dose cytosine arabinoside-(HAM). Consolidation was provided with myeloablative conditioning ( (en)
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Title
| - Prolonged survival of patients with peripheral T-Cell lymphoma after first-line intensive sequential chemotherapy with autologous stem cell transplantation
- Prolonged survival of patients with peripheral T-Cell lymphoma after first-line intensive sequential chemotherapy with autologous stem cell transplantation (en)
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skos:prefLabel
| - Prolonged survival of patients with peripheral T-Cell lymphoma after first-line intensive sequential chemotherapy with autologous stem cell transplantation
- Prolonged survival of patients with peripheral T-Cell lymphoma after first-line intensive sequential chemotherapy with autologous stem cell transplantation (en)
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skos:notation
| - RIV/61989592:15110/09:00009739!RIV10-MSM-15110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/09:00009739
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Peripheral T-cell lymphoma; PTCL; High-dose chemotherapy; Autologous transplantation; First line (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Faber, Edgar
- Indrák, Karel
- Jarošová, Marie
- Raida, Luděk
- Vondráková, Jana
- Procházka, Vít
- Kučerová, Ladislava
- Papajík, Tomáš
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http://linked.open...n/vavai/riv/zamer
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issn
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http://localhost/t...ganizacniJednotka
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