About: Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population

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About: Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Polymorphic gene variants in chemokine MCP-1 (CCL2) gene were determined by PCR-SSP in 151 patients with chronic angina pectoris (AP) and in 449 healthy subjects, both of Slovak ethnicity. The frequency of MCP-1-2518 GG homozygous individuals was increased in patients compared to control subjects (p=0.003); the increase was more pronounced in males and it was present both in early and late AP. The reported observation implicates the tested polymorphic MCP-1 gene variant in chronic AP, at least in patients of Slovak ethnicity. Polymorphic gene variants in chemokine MCP-1 (CCL2) gene were determined by PCR-SSP in 151 patients with chronic angina pectoris (AP) and in 449 healthy subjects, both of Slovak ethnicity. The frequency of MCP-1-2518 GG homozygous individuals was increased in patients compared to control subjects (p=0.003); the increase was more pronounced in males and it was present both in early and late AP. The reported observation implicates the tested polymorphic MCP-1 gene variant in chronic AP, at least in patients of Slovak ethnicity. (en)
Title	Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population (en)
skos:prefLabel	Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population (en)
skos:notation	RIV/61989592:15110/08:33115986!RIV12-MSM-15110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ME 856), Z(MSM6198959205)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Petřek, Martin Mrázek, František Petřková, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	357166
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/08:33115986
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DNA; gene; chemokines; atherosclerosis; myocardial-infarction (en)
http://linked.open.../riv/klicoveSlovo	DNA gene myocardial-infarction atherosclerosis chemokines
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[8BBFFEE99407]
http://linked.open...i/riv/nazevZdroje	Clinica Chimica Acta
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	http://linked.opendata.cz/resource/domain/vavai/projekt/ME%20856
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	392
http://linked.open...iv/tvurceVysledku	Mrázek, František Petřek, Martin Petřková, Jana Bucová, Mária Bernadič, Marián Lietava, Ján Buckingham, Thomas A
http://linked.open...n/vavai/riv/zamer	Studies of genes and molecular mechanisms involved in regulation of hematopoiesis, their clinical impact and targeted treatment
issn	0009-8981
number of pages	2 (xsd:int)
http://localhost/t...ganizacniJednotka	15110
is http://linked.open...avai/riv/vysledek of	Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population

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