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| rdf:type
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| Description
| - PURPOSE: Bmi-1 is a Polycomb group member which participates in many physiological processes as well as in a wide spectrum of cancers. The aim of this study was to investigate Bmi-1 expression in non-small cell lung cancer (NSCLC) in respect to clinicopathological features and therapeutic outcomes. METHODS: Immunohistochemical staining for Bmi-1 was performed on tissue microarrays (TMAs) constructed from 179 formalin-fixed and paraffin-embedded NSCLC samples (106 squamous, 58 adeno-, and 15 large cell carcinomas). Data were subject to statistical analysis by SPSS. RESULTS: Overall evaluation of all tumor cases showed that 20 (11.43%) were negative, 37 (21.14%) showed weak, 65 (37.14%) moderate and 57 (32.57%) strong nuclear positivity for Bmi-1. Statistical analysis of our data revealed that the expression of Bmi-1 was significantly higher in stage III (P = 10(-6)) and stage IV (P = 10(-5)) tumors compared to stages I and II tumors. The administration of adjuvant chemotherapy significantly increased D
- PURPOSE: Bmi-1 is a Polycomb group member which participates in many physiological processes as well as in a wide spectrum of cancers. The aim of this study was to investigate Bmi-1 expression in non-small cell lung cancer (NSCLC) in respect to clinicopathological features and therapeutic outcomes. METHODS: Immunohistochemical staining for Bmi-1 was performed on tissue microarrays (TMAs) constructed from 179 formalin-fixed and paraffin-embedded NSCLC samples (106 squamous, 58 adeno-, and 15 large cell carcinomas). Data were subject to statistical analysis by SPSS. RESULTS: Overall evaluation of all tumor cases showed that 20 (11.43%) were negative, 37 (21.14%) showed weak, 65 (37.14%) moderate and 57 (32.57%) strong nuclear positivity for Bmi-1. Statistical analysis of our data revealed that the expression of Bmi-1 was significantly higher in stage III (P = 10(-6)) and stage IV (P = 10(-5)) tumors compared to stages I and II tumors. The administration of adjuvant chemotherapy significantly increased D (en)
- Cíl: Bmi-1 je člen polykomb. skupiny, ktrá se účastní mnoha fyziologických procesů, stejně jako v širokém spektru druhů rakoviny. Cílem této studie bylo prozkoumat Bmi-1 expresi u nemalobuněčné rakoviny plic (NSCLC) s ohledme na klinickopatologické znaky a terapeutické závěry. (cs)
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| Title
| - Prognostic value of Bmi-1 oncoprotein expression in NSCLC patients: a tissue microarray study.
- Prognostická hodnota Bmi-1 onkoproteinové exprese u NSCLC pacientů: a tissue microarray study. (cs)
- Prognostic value of Bmi-1 oncoprotein expression in NSCLC patients: a tissue microarray study. (en)
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| skos:prefLabel
| - Prognostic value of Bmi-1 oncoprotein expression in NSCLC patients: a tissue microarray study.
- Prognostická hodnota Bmi-1 onkoproteinové exprese u NSCLC pacientů: a tissue microarray study. (cs)
- Prognostic value of Bmi-1 oncoprotein expression in NSCLC patients: a tissue microarray study. (en)
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| skos:notation
| - RIV/61989592:15110/08:00006169!RIV09-MZ0-15110___
|
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(NR8370), P(NR8425), S, Z(MSM6198959216)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/08:00006169
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Prognostic value of Bmi-1 oncoprotein expression (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Journal of cancer research and clinical oncology
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Ehrmann, Jiří
- Hajdúch, Marián
- Radová, Lenka
- Vrzalíková, Kateřina
- Kolář, Zdeněk
- Klein, Jiří
- Škarda, Jozef
- Kolek, Vitězslav
- Knížetová, Petra
- Fridman, E.
- Kopolovic, J.
- Murray, P. G.
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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| is http://linked.open...avai/riv/vysledek
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