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Description
| - The most significant precancerosis in the esophageal cancer is Barrett's esophagus. The risk of malignant transformationis determined primarily in accordance with the degree of dysplastic alterations of the mucosa. Indicationof %22preventive%22 extirpation of the esophagus should be supported by other factors, for example by detection of p53mutation or expression.The study reports on the evaluation of a group of 20 patients with Barrett's esophagus treated at the 1st Departmentof Surgery, the p53 level and its correlation with histological findings evaluated in these patients.A good correlation was found between the grade of Barrett's esophagus dysplasia and high p53 positivity. This correlationwas also confirmed by detection of early carcinoma in patients with %22preventive%22 extirpation of the esophagusdue to a high-grade dysplasia.Preliminary results show that examination of p53 level in specimens taken from the esophageal mucosa may behelpf
- The most significant precancerosis in the esophageal cancer is Barrett's esophagus. The risk of malignant transformationis determined primarily in accordance with the degree of dysplastic alterations of the mucosa. Indicationof %22preventive%22 extirpation of the esophagus should be supported by other factors, for example by detection of p53mutation or expression.The study reports on the evaluation of a group of 20 patients with Barrett's esophagus treated at the 1st Departmentof Surgery, the p53 level and its correlation with histological findings evaluated in these patients.A good correlation was found between the grade of Barrett's esophagus dysplasia and high p53 positivity. This correlationwas also confirmed by detection of early carcinoma in patients with %22preventive%22 extirpation of the esophagusdue to a high-grade dysplasia.Preliminary results show that examination of p53 level in specimens taken from the esophageal mucosa may behelpf (en)
- Nejsignifikantnější prekancerozi rakoviny jícnu je Baretův jícen. Riziko maligní transformace zavísí od stupně dysplastických změn sliznice. Studie opisuje na vzorku 20pacientů s Baretovým jícnem korelaci mezi stupněm dysplazie Baretovho jícnu a mutaci nebo změnenou expresí p53. (cs)
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Title
| - p53 - Prognostic factor of malignant transformation of barrett's esophagus.
- p53 - Prognostic factor of malignant transformation of barrett's esophagus. (en)
- p53 - prognostický faktor maligní transformace u Baretovho jícnu (cs)
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skos:prefLabel
| - p53 - Prognostic factor of malignant transformation of barrett's esophagus.
- p53 - Prognostic factor of malignant transformation of barrett's esophagus. (en)
- p53 - prognostický faktor maligní transformace u Baretovho jícnu (cs)
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skos:notation
| - RIV/61989592:15110/05:00001933!RIV06-MSM-15110___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/05:00001933
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Esophagus; Esophageal cancer; p53; Barrett's esophagus (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Bohanes, Tomáš
- Hajdúch, Marián
- Král, Vladimír
- Neoral, Čestmír
- Dráč, Petr
- Aujeský, René
- Klein, Jiří
- Vrba, Radek
- Ľubušská, Lucie
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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