About: Perspective nutraceutical - milk thistle extract with polyunsaturated fatty acids

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Byl sledován vliv silymarinu na lipidový profil v plazmě a antioxidační kapacitu séra. Dobrovolníci (muži, n=29) byli rozděleni do 2 skupin. Účastníci ve skupině 1 (n=17) dostávali 858 mg/den silymarinu a ´ve skupině 2 (n=12) placebo. Každému dobrovolníkovy byla odebráne krev (den 1., 30. a 60.). U skupiny 1 byl zjištěn nárůst HDL cholesterolu a Apo A1 a pokles celkového a LDL cholesterolu. (cs) A study was conducted to determine the effects of silymarin on plasma lipids and serum antioxidant capacity in man. 29 study volunteers were randomly divided into 2 groups of 17 and 12 and were given 858 mg/day of silymarin or placebo, respectively. 3 blood samples were taken from each participant, in days 1, 30 and 60. An increase in the trend in HDL-cholesterol , ApoA1 and a decrease of total cholesterol and LDL-cholesterol was foudn in the silymarin group in comparison with the placebo group. Changes in lipid peroxidation parameters between the silymarin group and the placebo group were statistically insignificant. Results suggest possibilities to use the combination of silymarin with currant oil as a nutraceutical, beneficial for the prevention of risk factors of atherosclerosis. A study was conducted to determine the effects of silymarin on plasma lipids and serum antioxidant capacity in man. 29 study volunteers were randomly divided into 2 groups of 17 and 12 and were given 858 mg/day of silymarin or placebo, respectively. 3 blood samples were taken from each participant, in days 1, 30 and 60. An increase in the trend in HDL-cholesterol , ApoA1 and a decrease of total cholesterol and LDL-cholesterol was foudn in the silymarin group in comparison with the placebo group. Changes in lipid peroxidation parameters between the silymarin group and the placebo group were statistically insignificant. Results suggest possibilities to use the combination of silymarin with currant oil as a nutraceutical, beneficial for the prevention of risk factors of atherosclerosis. (en)
Title	Perspective nutraceutical - milk thistle extract with polyunsaturated fatty acids Perspective nutraceutical - milk thistle extract with polyunsaturated fatty acids (en) Perspektivní nutraceutikum - extrakt z ostropestřce mariánského s polynenasycenými mastnými kyselinami (cs)
skos:prefLabel	Perspective nutraceutical - milk thistle extract with polyunsaturated fatty acids Perspective nutraceutical - milk thistle extract with polyunsaturated fatty acids (en) Perspektivní nutraceutikum - extrakt z ostropestřce mariánského s polynenasycenými mastnými kyselinami (cs)
skos:notation	RIV/61989592:15110/01:00006009!RIV09-MZ0-15110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NL6713), Z(MSM 151100003)
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Šimánek, Vilím ŠKOTTOVÁ, Nina Ulrichová, Jitka
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	690970
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/01:00006009
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Silybum marianum; human; LDL; HDL; cholesterol (en)
http://linked.open.../riv/klicoveSlovo	cholesterol human HDL LDL Silybum marianum
http://linked.open...ontrolniKodProRIV	[BF0F2F3047BD]
http://linked.open...i/riv/mistoVydani	Cambridge
http://linked.open...i/riv/nazevZdroje	Biologically-active Phytochemicals in Food. Analysis, Metabolism, Bioavailability and Function.
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Experimental pharmacology of antioxidants and hypolipidemics on the basis of standarized mixtures of polyphenols from Silybum marianum and Prunella vulgaris
http://linked.open...UplatneniVysledku	2001
http://linked.open...iv/tvurceVysledku	Ulrichová, Jitka Šimánek, Vilím Škottová, Nina
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20151100003
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	The Royal Society of Chemistry
https://schema.org/isbn	0-85404-806-5
http://localhost/t...ganizacniJednotka	15110

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