About: Factors that influence health-related quality of life in newly diagnosed patients with multiple myeloma aged >= 65 years treated with melphalan, prednisone and lenalidomide followed by lenalidomide maintenance: results of a randomized trial     Goto   Sponge   NotDistinct   Permalink

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  • In the MM-015 trial, melphalan - prednisone - lenalidomide followed by lenalidomide maintenance (MPR-R) signifcantly prolonged progression-free survival versus melphalan - prednisone (MP) in newly diagnosed patients with multiple myeloma aged >= 65 years. Health-related quality of life (HRQoL), a secondary endpoint of MM-015, was also improved with MPR-R. This sub-analysis evaluated the impact of individual predictive factors on HRQoL. Patients completed HRQoL questionnaires at baseline, every third cycle and at progressive disease (PD)/treatment discontinuation.
  • In the MM-015 trial, melphalan - prednisone - lenalidomide followed by lenalidomide maintenance (MPR-R) signifcantly prolonged progression-free survival versus melphalan - prednisone (MP) in newly diagnosed patients with multiple myeloma aged >= 65 years. Health-related quality of life (HRQoL), a secondary endpoint of MM-015, was also improved with MPR-R. This sub-analysis evaluated the impact of individual predictive factors on HRQoL. Patients completed HRQoL questionnaires at baseline, every third cycle and at progressive disease (PD)/treatment discontinuation. (en)
Title
  • Factors that influence health-related quality of life in newly diagnosed patients with multiple myeloma aged >= 65 years treated with melphalan, prednisone and lenalidomide followed by lenalidomide maintenance: results of a randomized trial
  • Factors that influence health-related quality of life in newly diagnosed patients with multiple myeloma aged >= 65 years treated with melphalan, prednisone and lenalidomide followed by lenalidomide maintenance: results of a randomized trial (en)
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  • Factors that influence health-related quality of life in newly diagnosed patients with multiple myeloma aged >= 65 years treated with melphalan, prednisone and lenalidomide followed by lenalidomide maintenance: results of a randomized trial
  • Factors that influence health-related quality of life in newly diagnosed patients with multiple myeloma aged >= 65 years treated with melphalan, prednisone and lenalidomide followed by lenalidomide maintenance: results of a randomized trial (en)
skos:notation
  • RIV/61988987:17110/14:A1501CGB!RIV15-MSM-17110___
http://linked.open...avai/riv/aktivita
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http://linked.open...iv/cisloPeriodika
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http://linked.open...aciTvurceVysledku
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  • 16365
http://linked.open...ai/riv/idVysledku
  • RIV/61988987:17110/14:A1501CGB
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  • Health-related quality of life (HRQoL); lenalidomide; multiple myeloma; minimal important difference (MID); QLQ-C30; QLQ-MY20 (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [0D863C74AA14]
http://linked.open...i/riv/nazevZdroje
  • Leukemia & Lymphoma
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 55
http://linked.open...iv/tvurceVysledku
  • Hájek, Roman
  • Delforge, Michel
  • Dimopoulos, Meletios A.
  • Kropff, Martin
  • Palumbo, Antonio
  • Petrucci, Maria Teresa
  • Lewis, Philip
  • Mei, Jay
  • Millar, Stefanie
  • Zhang, Jingshan
issn
  • 1042-8194
number of pages
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  • 17110
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