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  • Ve skupině 30 resekcí laryngu s invazivním spinocelulárním karcinomem studovali autoři nezměněné slizniční struktury v oblastech supraglotické, hrtanu a subglotické. Slizniční vzorky byly vzaty a jejich vyšetřování bylo založeno na standardních dysplastických změnách s využitím základního barvení hematoxylin - eosin a jiných speciálních metod. Imunohistochemické vyšetření ( p53, Ki67, p16) ukázala pozitivitu pouze ve vyšším stupni dysplázie a v karcinomu in situ. Chronické zánětlivé změny byly objeveny častěji. Autoři navrhli, že zásadní příčina nemůže být podhodnocená společně s jinými rizikovými faktory. (cs)
  • In a group of 30 laryngeal resections with invasive spinocellular carcinoma the authors studied the unchanged mucous structures in the supraglottic, glottic and subglottic areas. Mucosal samples were taken and their examination was focused on standard dysplastic changes using basic colouring hematoxylin-eosine and other special methods. Immmunohistochemical examination (p53, Ki 67, p16) showed positivity only in advanced stage dysplasia and in carcinoma in situ. Chronic inflammatory changes were commonly found. The authors suggest that vital etiology should not be underestimated along with other risk factors.
  • In a group of 30 laryngeal resections with invasive spinocellular carcinoma the authors studied the unchanged mucous structures in the supraglottic, glottic and subglottic areas. Mucosal samples were taken and their examination was focused on standard dysplastic changes using basic colouring hematoxylin-eosine and other special methods. Immmunohistochemical examination (p53, Ki 67, p16) showed positivity only in advanced stage dysplasia and in carcinoma in situ. Chronic inflammatory changes were commonly found. The authors suggest that vital etiology should not be underestimated along with other risk factors. (en)
Title
  • Carcinoma Precursors in Laryngeal Resections
  • Carcinoma Precursors in Laryngeal Resections (en)
  • Prekurzory karcinomu v resekátech jícnu (cs)
skos:prefLabel
  • Carcinoma Precursors in Laryngeal Resections
  • Carcinoma Precursors in Laryngeal Resections (en)
  • Prekurzory karcinomu v resekátech jícnu (cs)
skos:notation
  • RIV/61988987:17110/06:A0900GGZ!RIV09-MSM-17110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S
http://linked.open...iv/cisloPeriodika
  • 150
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 467774
http://linked.open...ai/riv/idVysledku
  • RIV/61988987:17110/06:A0900GGZ
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • larynx; histopathology; dysplasia; immunohistochemistry (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [3CE220B41D73]
http://linked.open...i/riv/nazevZdroje
  • Biomed Pap Med univ Palacky Olomouc
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 1
http://linked.open...iv/tvurceVysledku
  • Mrázek, Jiří
  • Horáček, Jaroslav
  • Váňová, J.
issn
  • 1213-8118
number of pages
http://localhost/t...ganizacniJednotka
  • 17110
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